Development of Computerized Multicomponent Cognitive Stimulation for Improving Cognitive Functions in Older Adults with Mild Cognitive Impairment: A Multimodal Investigation Using Neuropsychological and EEG/ERP Assessment

Phase 2

Completed

• Conditions: Older adults with mild cognitive impairment (MCI); mild cognitive impairment; MCI

• Registration Number: TCTR20230829004
• Lead Sponsor: ational Research Council of Thailand (NRCT)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-08-29
• Study Completion: 2023-12-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 93

Inclusion Criteria

1) Thai native speakers.
2) Age more than 60 years.
3) The performances in objective memory impairment are based on the Montreal Cognitive Assessment (MoCA) and The Clinical Dementia Rating (CDR) scores
4) Right-handed according to the Edinburgh Handedness Inventory.
5) Normal color vision according to the Ishihara Plate Test.
6) No chronic illness, deafness, blindness, or major neurological disorder.
7) Not demented
8) Able to read with comprehension
9) Able to use computer devices.

Exclusion Criteria

1) Participants diagnosed with dementia.
2) Participants with systemic illness.
3) Participants refusal to participate.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
earning and memory End of the intervention Paired associate learning test,Executive End of the intervention Wisconsin card sorting test,Language End of the intervention Verbal fluentcy test,Psychomotor End of the intervention Reaction time tests (Simple and Choice),Visuospatial skills End of the intervention Mental rotation and Corsi block tapping tests,Multisensory integration End of the intervention Sound-Induced Flash Illusion (SIFI) test,EEG End of the intervention alpha, theta, beta, and delta,ERP End of the intervention N100, P200, P300, N400 and P600,Global cognitive function End of the intervention Montreal Cognitive Assessment,Emotions (Depression) End of the intervention Geriatric Depression Scale,Emotions (Anxiety) End of the intervention State-Trait Anxiety Inventory

Secondary Outcome Measures

Name	Time	Method
Quality of Life End of the intervention Quality of Life and Activities of Daily Life Index tests