Effect of Dexmedetomidine for prevention of postoperative Nausea and Vomiting
Not Applicable
- Conditions
- Complications of General Anesthesia..Other specified complications of surgical and medical care, not elsewhere classified.
- Registration Number
- IRCT2016092629993N1
- Lead Sponsor
- Vice chancellor for research, Arak University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 105
Inclusion Criteria
All adult patients at the age of 20-50 years; Patients with ASA class I -II; absence of drug abuse and Opioid addiction; Patients who fulfil Apfel criteria. Exclusion criteria: being allergic to drugs under study; Using of antiemetic drugs 48 hours before operation for any reason; BMI up to 35 kg / m2; pregnancy; not willing to participate in the study.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ausea and Vomiting. Timepoint: First 24 hours post Operation (every 6 houre). Method of measurement: Ask from the Patient based on the VAS score.
- Secondary Outcome Measures
Name Time Method Blood pressure. Timepoint: Before prescribing intervener Drugs (T0), At 5 minutes after prescribing (T1), At 30 minutes after prescribing (T2), At 5 minutes after Extubation (T3), At the time of enterance to recovery (T4). Method of measurement: By Sphygmomanometer, mmHg.;Pulse rate. Timepoint: Before prescribing intervener Drugs (T0), At 5 minutes after prescribing (T1), At 30 minutes after prescribing (T2), At 5 minutes after Extubation (T3), At the time of enterance to recovery (T4). Method of measurement: Counting in one minute.;O2 Saturation. Timepoint: Before Operation. Method of measurement: Pulse Oximetery.