Dependence on Analgesics in Chronic Non-cancer Pain

Completed

• Conditions: Pain, Chronic
• Interventions: Behavioral: Questionnaire

• Registration Number: NCT03346408
• Lead Sponsor: University Hospital, Toulouse

Brief Summary

The identification of an addiction to opioid analgesics has become strong recommendation for the purpose of improving the clinical management of the patients. However, the success of the patient's clinical management, in terms of analgesia and treatment of drug dependence, rests on the acceptance of this management by the patient himself. The main objective of this study is to evaluate the factors associated to the discrepancy between the assessment of dependence on analgesic drugs by the algologist and the perception that the patient with non-cancer chronic pain has of this dependence.

Detailed Description

The long-term use of opioid analgesics for the treatment of chronic non-cancer pain exposes patients to the risk of developing drug dependence on these psychoactive drugs with loss of control of their use. In general medicine as well as in algology consultation, the identification of an addiction to opioid analgesics (and even misuse as a gateway to addiction) have thus become strong recommendations for the purpose of improving the management of the patients. However, the success of the patient's clinical management, in terms of analgesia and treatment of drug dependence, rests on the acceptance of this management by the patient himself.

The discrepancy between the assessment of drug dependence on analgesic drugs by the algologist and the perception that the patient has of this dependence will be investigated through a multicentre cross-sectional descriptive survey performed in pain treatment centres in France.

In addition to opioid analgesics, other pharmacological classes used for analgesic use will be investigated as they are concerned with the development of drug dependence. This is particularly the case for gabapentins.

Study Timeline

• Study Start: 2017-11-04
• Study First Submitted: 2017-11-10
• Study First Submitted QC: 2017-11-14
• Study First Posted: 2017-11-17
• Primary Completion: 2018-11-19
• Study Completion: 2018-12-18
• Status Verified: 2024-05
• Last Update Submitted: 2024-05-28
• Last Update Posted: 2024-05-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 220

Inclusion Criteria

• suffering from chronic non-cancer pain,
• taking at least one analgesic medication

Exclusion Criteria

• Patient minor or major protected by the law (under tutelage),
• Patient with chronic pain of cancerous origin,
• Opposition of the patient to be included in the study,
• Patient not having the overall skills to complete a self-questionnaire: major difficulties in understanding the French language and / or reading / writing difficulties.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients	Questionnaire	data collection obtained from patient (self-questionnaire) and algologist physician (questionnaire).

Primary Outcome Measures

Name	Time	Method
discrepancy between the assessment of dependence on analgesic drugs by the algologist and the perception of the patient	Baseline	The patients will complete a self-questionnaire and the algologist physician will fill another questionnaire.

Secondary Outcome Measures

Name	Time	Method
Consumption drugs	Baseline	Patient questionnaire for associated drug
Anxiety	Baseline	Hospital Anxiety and Depression Scale (HAD Scale)

Trial Locations

Locations (7)

University Hospital Bordeaux; 🇫🇷 Bordeaux, France

University Hospital Montpellier; 🇫🇷 Montpellier, France

University Hospital Marseille; 🇫🇷 Marseille, France

University Hospital Clermont-Ferrand; 🇫🇷 Clermont-Ferrand, France

University Hospital Limoges; 🇫🇷 Limoges, France

University Hospital Nice; 🇫🇷 Nice, France

University HospitalToulouse; 🇫🇷 Toulouse, France