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Clinical Trials/SLCTR/2023/016
SLCTR/2023/016
Recruiting
Phase 2

A double-blind randomized controlled trial to investigate the effectiveness and safety of Retinyl Palmitate in patients with chronic Achilles tendinopathy.

Regenall (UK)0 sitesTBD
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ConditionsAchilles tendinopathy

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Achilles tendinopathy
Sponsor
Regenall (UK)
Status
Recruiting
Last Updated
last year
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
last year
Study Type
Interventional

Investigators

Sponsor
Regenall (UK)

Eligibility Criteria

Inclusion Criteria

  • •a. Both male and female \>\=18 years
  • •b. Participating in competitive sport
  • •c. Confirmed clinical and /or imaging\-based (MRI or Grey\-scale ultrasound) diagnosis of chronic mid\-portion Achilles tendinopathy
  • •d. Unable to regularly participate in their sport due to Achilles tendinopathy for the past minimum 3 months but no longer than 6 months

Exclusion Criteria

  • •a.Previous Achilles tendon rupture on the affected side
  • •b.Previous Achilles tendon surgery on the affected side
  • •c.History of traumatic tears
  • •d.Unable or unwilling to adhere to standardised rehabilitation programme
  • •e.Previous history of arrythmias
  • •f.History of myocardial infarction or unstable angina within the past 12 months
  • •g.History of retinopathy
  • •h.Participant is already taking Vitamin A supplementation or other retinoid derivatives
  • •i.Participant is taking tetracyclines
  • •j.Known hereditary thrombophilia (Factor V Leiden, Protein C/ S deficiency, anti\-phospholipid or anti\-cardiolipin antibodies)

Outcomes

Primary Outcomes

Not specified

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