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Clinical Trials/NCT05469412
NCT05469412
Completed
Not Applicable

To Compare Pharmacological and Non-Pharmacological Interventions (Use of Technology) For Alleviating Preoperative Anxiety In Children Undergoing General Anesthesia In A Tertiary Care Hospital Of Pakistan: A Randomized Controlled Trial.

Aga Khan University1 site in 1 country84 target enrollmentMarch 20, 2023
InterventionsiPad®Midazolam

Overview

Phase
Not Applicable
Intervention
iPad®
Conditions
Anxiety and Fear
Sponsor
Aga Khan University
Enrollment
84
Locations
1
Primary Endpoint
modified Yale Preoperative Anxiety Scale
Status
Completed
Last Updated
last year

Overview

Brief Summary

The purpose of this study is to find out any beneficial effects of electronic devices over preoperative pharmacological intervention in the preoperative period.

Detailed Description

Preparation for surgery with the induction of general anesthesia can be a stressful experience for a child. Preoperative anxiety can prolong induction of anesthesia and postoperative recovery, as well as increasing the risk of postoperative delirium, pain, and analgesic use. Pharmacological interventions are associated with increased cost to the hospital, potential surgical delay while waiting for the medication to take effect, and delayed discharge from the recovery room. Non-pharmacological modalities comprise education, behavioral techniques, parental presence at induction of anesthesia, and using technology including cellular phones and tablets/iPad, with each category including an array of effective strategies for reducing anxiety.

Registry
clinicaltrials.gov
Start Date
March 20, 2023
End Date
April 1, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Muhammad Asghar Ali

Associate Professor

Aga Khan University

Eligibility Criteria

Inclusion Criteria

  • Children aged between 2 and 12 years old
  • ASA I and II
  • Informed consent signed by parents or legal guardians

Exclusion Criteria

  • Previous exposure to surgery
  • Contraindication to midazolam
  • Patients with developmental delay
  • Patients with significant visual/hearing problems

Arms & Interventions

Interventional group

Standard management combined with distraction by using technology (Tablets/iPads).

Intervention: iPad®

Control group

Standard management combined with pharmacological intervention (oral midazolam 0.5 mg/kg) administered at least 30 min before surgery (maximum 20mg).

Intervention: Midazolam

Outcomes

Primary Outcomes

modified Yale Preoperative Anxiety Scale

Time Frame: Day 1

The instrument contains 27 items in 5 categories that indicate preoperative anxiety in children: activity, emotional expressivity, state of arousal, vocalization, and use of parents. Scores range from 23.33 to 100, with higher values indicating higher anxiety.

Study Sites (1)

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