Post operative pain relief using Buprenorphine and Ketorolac

Not yet recruiting

• Conditions: Acute appendicitis with localizedperitonitis, (2) ICD-10 Condition: K400||Bilateral inguinal hernia, with obstruction, without gangrene, (3) ICD-10 Condition: K811||Chronic cholecystitis,

• Registration Number: CTRI/2023/11/059855
• Lead Sponsor: Kameshwar ownself

Brief Summary

Pain is a major post-operative complication worldwide, which impairs normal body performance andincreases post-operative morbidity, hospitalization and susceptibility to infections which also can lead tochronic pain development.To compare the analgesicpotential of Buprenorphine and Ketorolac for postoperative pain relief.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-12
• Last Update Posted: 2023-06-11

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 140

Inclusion Criteria

1.ASA I or II 2.Patients scheduled for elective abdomen surgeries under general anesthesia 3.Age: 20-60 years.

Exclusion Criteria

• 1.Patient refusal.
• 2.Allergy or hypersensitivity to Buprenorphine and Ketorolac.
• 3.Pregnant and Lactating women 4.Patient having a.
• Uncontrolled hypertension/diabetes mellitus.
• History of chronic pain.
• Psychiatric disease.
• Alcohol or drug usage.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
2.Time duration needed for the usage of rescue analgesic	Baseline ( before the surgery), | Intra operative period, | Immediate post operative period-0 minutes | 1 hour after post operative period, | 2 hours after post operative period, | 4 hours after post operative period, | 6 hours after post operative period, | 8 hours after post operative period, | 12 hours after post operative period.
1.Dose of the study drug	Baseline ( before the surgery), | Intra operative period, | Immediate post operative period-0 minutes | 1 hour after post operative period, | 2 hours after post operative period, | 4 hours after post operative period, | 6 hours after post operative period, | 8 hours after post operative period, | 12 hours after post operative period.

Secondary Outcome Measures

Name	Time	Method
Time duration for rescue analgesic	At the end of surgery 0 hours,

Trial Locations

Locations (1)

Sri Muthukumaran Medical College Hospital and Research Institute; 🇮🇳 Chennai, TAMIL NADU, India

Sri Muthukumaran Medical College Hospital and Research Institute

🇮🇳Chennai, TAMIL NADU, India

Kameshwar

Principal investigator

9176191069

speak2kamesh@gmail.com