ABICUS trial
Not Applicable
Completed
- Conditions
- Musculoskeletal surgeryMusculoskeletal Diseases
- Registration Number
- ISRCTN67230654
- Lead Sponsor
- eurotechnics Limited (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
1. Participant is willing and able to give informed consent for participation in the study
2. Male or female, aged 18 years to 65 years
3. Diagnosed with articular cartilage defect in the knee as assessed on MRI scan
4. No other significant medical comorbidities (medical diseases)
5. Able and willing to comply with all study requirements
Exclusion Criteria
1. Generalised and/or inflammatory arthritis
2. Active joint inflammation
3. Obvious deformity in the knee
4. Age below 18 and over 65 years
5. Significant medical comorbidities
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical function, measured by the mean Lysholm, Knee injury and Osteoarthritis Outcome Score (KOOS) and International Knee Documentation Committee (IKDC) scoring scales at 6 weeks, 3 months, 6 months, 1 and 2 years post-operatively
- Secondary Outcome Measures
Name Time Method Cartilage growth, assessed by MRI [Magnetic resonance Observation of CArtilage Repair Tissue (MOCART) score] at 1 and 2 years post-operatively