Increasing Uptake of Colorectal Cancer Screening in Ontario

Not Applicable

Completed

• Conditions: Colorectal Disorders
• Interventions: Other: FOBT kit; Other: Mailed invitation

• Registration Number: NCT01629004
• Lead Sponsor: Sunnybrook Health Sciences Centre

Brief Summary

The investigators hope to determine whether the addition of an FOBT kit and educational materials to a second mailed invitation compared to a second mailed invitation alone increases use of appropriate screening tests (FOBT for average risk or colonoscopy if increased risk) by eligible persons within 6 months of the second mailing in: (1)Non-responders to an initial mailed CRC screening invitation from their family physician and, (2)Those who responded to the initial mailed CRC screening invitation and are due for repeat screening (i.e., "recall" patients). In addition, the investigators will also explore the impact of the investigators intervention in likely under-screened groups such as those living in more remote areas of the province and those with low socio-economic status as well as assessing the cost-effectiveness of this strategy.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-04
• Study First Submitted: 2012-06-25
• Study First Submitted QC: 2012-06-26
• Study First Posted: 2012-06-27
• Primary Completion: 2013-12
• Study Completion: 2013-12
• Status Verified: 2014-12
• Last Update Submitted: 2014-12-19
• Last Update Posted: 2014-12-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 5155

Inclusion Criteria

• Recipients of a mailed CRC screening invitation through the CCO Invitation Pilot project
• No OHIP record of completion of FOBT since initial mailing (Non-responders arm only)
• No OHIP of 'CRC Cancer Screening Exclusion' tracking code since initial mailing (Non-responders arm only)
• An OHIP record of completion of FOBT 6 months since initial mailing (Recall arm only)
• Negative result according to LRT or if not in LRT, no record of interval colonoscopy in CIRT or OHIP (Recall arm only)

Exclusion Criteria

• Age greater than 74 years at time of mailing
• Interval diagnosis of colorectal cancer
• Interval colonoscopy or flexible sigmoidoscopy
• Interval departure from Pilot physician's practice
• Death
• Presently institutionalized
• Physician has declined participation in the study
• Interval record of repeat FOBT (Recall arm only)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
Recall patients	Mailed invitation	Those who responded to the initial mailed CRC screening invitation and are now due for repeat screening (i.e., "recall" patients). FOBT kit. Mailed invitation.
Non-responders	FOBT kit	Non-responders to an initial mailed CRC screening invitation from their family physician. FOBT kit. Mailed invitation.
Non-responders	Mailed invitation	Non-responders to an initial mailed CRC screening invitation from their family physician. FOBT kit. Mailed invitation.
Recall patients	FOBT kit	Those who responded to the initial mailed CRC screening invitation and are now due for repeat screening (i.e., "recall" patients). FOBT kit. Mailed invitation.

Primary Outcome Measures

Name	Time	Method
Uptake of appropriate CRC screening	Within 6 months of the mailing	The primary outcome will be the uptake of appropriate screening (FOBT testing or if there is a positive family history, of colonoscopy) within 6 months of the mailing as determined by from OHIP and CCO data.

Secondary Outcome Measures

Name	Time	Method
Uptake of lower gastrointestinal investigations	Within 12 months of the mailing	The secondary outcome will be the uptake of lower gastrointestinal investigations (colonoscopy for an indication other than family history or colonoscopy done outside of CIRT, flexible sigmoidoscopy, barium enema) within 12 months, respectively, of the mailing as determined by the administrative data (CIRT, OHIP procedure or radiology code).

Trial Locations

Locations (1)

Sunnybrook HSC; 🇨🇦 Toronto, Ontario, Canada