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The Impact of Fish Oil Supplementation on Muscle Growth in Older Me

Conditions
oss of skeletal muscle mass and strength with aging, also termed sarcopenia
Registration Number
NL-OMON26123
Lead Sponsor
McMaster University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
13
Inclusion Criteria

1)Male

2)Age 65-80 y

Exclusion Criteria

1)Medical, orthopedic, or psychiatric concern that, in the opinion of the investigators, would compromise the ability to comply with the study requirements

2)History of cancer within the last 5 years, except basal cell carcinoma, non-squamous skin carcinoma, prostate cancer or carcinoma in situ with no significant progression over the past 2 years

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Daily muscle protein synthesis rates assessed using D2O before and after 4 weeks of fish oil supplementation
Secondary Outcome Measures
NameTimeMethod
1)Muscle and blood lipid composition before, during, and after fish oil supplementation<br /><br>2)Plasma markers of inflammatory state before, during, and after fish oil supplementation<br /><br>3)Insulin sensitivity as assessed by oral glucose tolerance test following the ingestion of 75 g glucose before and after 4 weeks of fish oil supplementation<br>
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