To compare the effects of local application of hyaluronic acid gel and chlorhexidine gel in treatment of patients with gum disease.

Phase 4

Not yet recruiting

• Conditions: Other infectious disease,

• Registration Number: CTRI/2019/01/017269
• Lead Sponsor: Dr JAAHNAVI LANKA

Brief Summary

The remarkably high biocompatibility of hyaluronic acid gel is a  pivot for its gain in popularity as a bio material scaffold in tissue engineering research and its use as a dermal filler in cosmetic procedures. in the field of dentistry the availability of hyaluronic acid in India commercially is rather less. Hyaluronic acid is highly biocompatible and no side effects are reported. Hence more research is needed for developing its use in Periodontal therapy in India.Therefore the aim of this study is to evaluate the different commercially available formulations of hyaluronic acid gel using it in Periodontal therapy.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-02-23
• Last Update Posted: 2020-01-21

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 72

Inclusion Criteria

• patients with minimum of 18 natural teeth in mouth 2.
• chronic periodontitis patients with probing pocket depth >/ 5mm in minimum of three teeth per quadrant bilaterally in the maxillary arch.

Exclusion Criteria

• 1.use of local or systemic antimicrobial agents 6 months prior to study.
• previous periodontal therapy during last 6 months.
• 3.pregnancy 4.
• smokers 5.regular users of mouth wash.
• 6.chronic alcoholics 6.patients using vitamin supplements, anti inflammatory agents in past 3 months.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. clinical parameters between the different concentrations of hyaluronic acid gel are compared at 3 months.	1. clinical parameters between the different concentrations of hyaluronic acid gel are compared at 3 months.

Secondary Outcome Measures

Name	Time	Method
to evaluate drug release of hyaluronic acid gel released from gingival crevicular fluid after the treatment.	4 hours, 2 weeks.

Trial Locations

Locations (1)

Manipal College of Dental Sciences; 🇮🇳 Udupi, KARNATAKA, India

Manipal College of Dental Sciences

🇮🇳Udupi, KARNATAKA, India

Dr Jaahnavi Lanka

Principal investigator

7036437357

dr.jaahnavi.lanka@gmail.com