Skip to main content
Clinical Trials/NCT05003349
NCT05003349
Completed
Not Applicable

Additional Effect of Pain Neuroscience Education, Motor Imagery and Action Observation in Patients With Chronic Temporomandibular Disorders. A Randomized Controlled Trial

University of Gran Rosario1 site in 1 country50 target enrollmentAugust 31, 2021
ConditionsTMD

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
TMD
Sponsor
University of Gran Rosario
Enrollment
50
Locations
1
Primary Endpoint
Change in Craneofacial pain and disability inventory.
Status
Completed
Last Updated
3 months ago

Overview

Brief Summary

The objective of this study will be to verify the additional effect of Pain Neuroscience Education, Motor Imagery and Action Observation on primary outcomes pain intensity and craniofacial pain and disability in patients with chronic temporomandibular disorders (TMD). The secondary outcomes will be pressure pain threshold, temporal summation, conditioned pain modulation, central sensibilization, pain catastrophizing, kinesiophobia. This study will be a doble-blinded randomized clinical trial comprising a sample of 50 participants with orofacial pain of both genders and aged between 18 and 60 years. Subjects will undergo a screening process to identify those presenting a diagnosis of painful TMD confirmed by the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD), and then they will be randomized into two groups (G1: Occlusal Splint, Counselling and Jaw and Neck Exercises vs. (G2: Occlusal Splint, Jaw and Neck Exercises plus Pain Neuroscience Education, Motor Imagery and Action Observation). These volunteers will be recruited from the Alisos Group Dentistry Clinic and University of Gran Rosario, (Rosario, Argentina). All patients will wear an occlusal splint designed by dentists. The interventions will be administered twice a week for 5 weeks by a single therapist. Subsequently, patients will be given instructions to perform the exercises at home for 5 weeks. Primary and secondary outcomes will be measured at baseline, 6 weeks and 12 weeks, and at 3 months after the end of treatment (follow-up). All the evaluations will be performed by a blinded physiotherapist.

Registry
clinicaltrials.gov
Start Date
August 31, 2021
End Date
January 12, 2026
Last Updated
3 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
University of Gran Rosario
Responsible Party
Principal Investigator
Principal Investigator

Mauro Barone

PT

University of Gran Rosario

Eligibility Criteria

Inclusion Criteria

  • A diagnosis of painful TMD using the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD)
  • A history of orofacial pain during at least three months prior to the study
  • Age ranging between 18 to 65 years, both genders.

Exclusion Criteria

  • Patients with neurological disorders (neuropathic pain or neurodegenerative disease), whiplash associated disorders, specific neck pain (radicular pain), recent dental or physical therapy. If patients are taking medication to relieve pain during the study, they will be encouraged to report it.

Outcomes

Primary Outcomes

Change in Craneofacial pain and disability inventory.

Time Frame: At baseline, then at six, twelve weeks, and 3 months follow-up.

The Craneofacial pain and disability inventory (CF-PDI) is a self-administered questionnaire that has been designed to obtain information on how pain in the orofacial region affects the patient's daily life. It consists of 21 items, with the final score ranging from 0 to 63 points. Each question is scored on a 4-point ordinal scale, ranging from 0 to 3. A higher score reflects higher pain and disability levels.

Change in Pain intensity.

Time Frame: At baseline, then at six, twelve weeks, and 3 months follow-up.

The Numerical Pain Rating Scale (NPRS) will be used to assess pain intensity. This scale consists in a sequence of numbers from 0 to 10, in which 0 represents "no pain" and 10 represents "worst pain imaginable".

Secondary Outcomes

  • Change in Pressure Pain Threshold.(At baseline, then at six, twelve weeks, and 3 months follow-up)
  • Change in Central Sensibilization Inventory.(At baseline, then at six, twelve weeks, and 3 months follow-up)
  • Change in Conditioned Pain Modulation.(At baseline, then at six, twelve weeks, and 3 months follow-up)
  • Change in Temporal Summation.(At baseline, then at six, twelve weeks, and 3 months follow-up)
  • Change in Spanish version of the Tampa Scale of Kinesiophobia for Temporomandibular. Disorders(At baseline, then at six, twelve weeks, and 3 months follow-up)
  • Change in Pain Catastrophizing Scale(At baseline, then at six, twelve weeks, and 3 months follow-up)
  • Change in Home exercise adherence(Between the sixth and twelfth week (once per week))

Study Sites (1)

Loading locations...

Similar Trials