Post-surgical stress response after radical prostatectomy

• Conditions: Radical prostatectomy using the DA-Vinci surgical system; Malignant neoplasm of prostate; C61

• Registration Number: DRKS00024975
• Lead Sponsor: Klinik für Anästhesiologie und Operative Intensivmedizin, Universitätsklinikum Mannheim

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-04-20
• Study Completion: 2022-09-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: Male
• Target Recruitment: 41

Inclusion Criteria

Subjects are scheduled for prostatectomy using the DA-Vinci surgical system, Subjects do not have type 1 or type 2 Diabetes mellitus, Subjects are between 18 and 85 years of age

Exclusion Criteria

Excluded from the study are minors, incapacitated adults, subjects with cardiac conduction disorders, subjects with postoperative infection, and patients who disagree with the above inclusion criteria or do not give consent for inclusion in the study.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The aim of the study is to find out more about the course of the postoperative stress response. To this end, we will first collect data on the surrogate parameters of the post-surgical stress response mentioned above, including heart rate variability, interleukin 6 and 10, and C-reactive protein, and then examine their correlation. <br>Another aim is to investigate whether subjectively perceived pain, measured by the Numeric Rating Scale (NRS), correlates with HRV and whether the courses of the individual surrogate parameters correlate with mood, measured by validated questionnaires.<br>

Secondary Outcome Measures

Name	Time	Method
The courses of the surrogate parameters will be examined.