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Glycemic Index in Subjects With Diabetes Mellitus Insulin Requesting

Not Applicable
Completed
Conditions
Diabetes Mellitus, Type 2
Interventions
Other: High glycemic index
Other: Low glycemic index
Registration Number
NCT02881164
Lead Sponsor
Universidad de Valparaiso
Brief Summary

To evaluate the acute effect of a low and high glycemic index breakfast on the glycemic response and satiety in subjects with type 2 diabetes mellitus under intensive insulin therapy.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
10
Inclusion Criteria
  • Subjects with type 2 diabetes mellitus diagnosis.
  • Minimum period of six months under intensive insulin therapy.
  • Fast insulin prescription before breakfast.
  • 35 and 70 years of age.
  • BMI between 25 and 39.9 Kg/m2.
  • HbA1c less than or equal to 10 % (86mmol/mol)
  • Menopausal women under hormone replacement therapy
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Exclusion Criteria
  • Pregnant women.
  • Puerperal women.
  • Subjects with neurological disease, endocrine disorder no treatment, kidney disease in stage IV or V, cancer, liver disease, chronic obstructive pulmonary disease, human immunodeficiency virus.
  • Subjects with history of stroke, acute myocardial infarction or gastrointestinal resection.
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Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
High glycemic index breakfastHigh glycemic indexHigh glycemic index breakfast (GI=80)
Low glycemic index breakfastLow glycemic indexLow glycemic index breakfast (GI=45)
Primary Outcome Measures
NameTimeMethod
Glycemia-15 up to 120 minutes

Glycemia (mg/dL) to -15, 30, 60 and 120 minutes, with respect to breakfast intake

SatietyUp to 120 minutes

Visual Analog Scale (VAS) was applied immediate and tardy postprandial (two hours after eating breakfast).

Secondary Outcome Measures
NameTimeMethod
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