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Clinical Trials/NCT06246994
NCT06246994
Not yet recruiting
Not Applicable

Predictors of Mortality Among Ventilator Associated Pneumonia Patients

Assiut University0 sites140 target enrollmentMarch 2024
ConditionsPneumonia

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pneumonia
Sponsor
Assiut University
Enrollment
140
Primary Endpoint
Mortality rate at 28 days.
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

In this context, this study aims to explore the risk factors for mortality from VAP in respiratory ICU.

Detailed Description

Pneumonia is the most common infection treated within ICUs and carries significant mortality risk . Ventilator-associated pneumonia (VAP) is a specific form of nosocomial pneumonia occurring in patients greater than 48 hours after intubation and the initiation of mechanical ventilation . VAP is considered a leading cause of morbidity and mortality among intensive care unit infections. Despite various preventive measures, the incidence of VAP remains high . In studies, VAP-related mortality is 14-70% . It is contemplated that there are independent risk factors, increasing VAP-related mortality . However, the question of which factors are associated with early or late mortality in patients with VAP diagnosis, remains unanswered. Early identification and understanding of the etiology of VAP in the ICU is essential to prevent mortality and morbidity.

Registry
clinicaltrials.gov
Start Date
March 2024
End Date
September 2025
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Marwa Hussien kilany

principal investigator

Assiut University

Eligibility Criteria

Inclusion Criteria

  • This study will enroll:
  • adult participants over 18 years old who had undergone mechanical ventilation for longer than 48 hours.
  • Only the first episode of VAP for each patient will be included.

Exclusion Criteria

  • Patients who are less than 18 years old.
  • Pneumonia diagnosed before mechanical ventilation.

Outcomes

Primary Outcomes

Mortality rate at 28 days.

Time Frame: 28 days

Evaluation of number of dead patients from vap wihin 28 days of infection and

Percentage of risk factors of VAP mortality.

Time Frame: 28 days

Search for risk factors for mortality of vap wihin 28 days of infection.

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