NCT00316433
Terminated
Phase 2
Phase II Study of Oxaliplatin and CPT-11 as First Line Treatment for Extensive Stage Small Cell Lung Cancer
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Small Cell Lung Cancer
- Sponsor
- Swedish Medical Center
- Enrollment
- 24
- Locations
- 1
- Status
- Terminated
- Last Updated
- 19 years ago
Overview
Brief Summary
The purpose of this study is to determine the safety and effectiveness of the combination of oxaliplatin and irinotecan (CPT-11) in patients with previously untreated, advanced small cell lung cancer.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Previously untreated extensive small cell lung cancer
- •No prior chemotherapy
- •No prior radiotherapy except for the treatment of brain metastases
Exclusion Criteria
- •Prior treatment for extensive stage small cell lung cancer
- •Known hypersensitivity to any of the components of oxaliplatin or CPT-11
- •Greater than grade 2 peripheral neuropathy
- •Known HIV or Hepatitis B or C (active, previously treated or both)
Outcomes
Primary Outcomes
Not specified
Study Sites (1)
Loading locations...
Similar Trials
Completed
Phase 1
Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or LymphomasChildhood Burkitt LymphomaChildhood Central Nervous System Germ Cell TumorChildhood Diffuse Large Cell LymphomaChildhood Grade III Lymphomatoid GranulomatosisChildhood Immunoblastic Large Cell LymphomaRecurrent Childhood Brain Stem GliomaRecurrent Childhood Cerebellar AstrocytomaRecurrent Childhood Cerebral AstrocytomaRecurrent Childhood EpendymomaRecurrent Childhood Grade III Lymphomatoid GranulomatosisRecurrent Childhood Large Cell LymphomaRecurrent Childhood Liver CancerRecurrent Childhood Lymphoblastic LymphomaRecurrent Childhood Malignant Germ Cell TumorRecurrent Childhood MedulloblastomaRecurrent Childhood RhabdomyosarcomaRecurrent Childhood Small Noncleaved Cell LymphomaRecurrent Childhood Soft Tissue SarcomaRecurrent Childhood Supratentorial Primitive Neuroectodermal TumorRecurrent Childhood Visual Pathway GliomaRecurrent Colon CancerRecurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal TumorRecurrent MelanomaRecurrent Nasopharyngeal CancerRecurrent NeuroblastomaRecurrent OsteosarcomaRecurrent Wilms Tumor and Other Childhood Kidney TumorsRecurrent/Refractory Childhood Hodgkin LymphomaUnspecified Childhood Solid Tumor, Protocol SpecificNCT00101270National Cancer Institute (NCI)24
Completed
Phase 1
Combination Chemotherapy in Treating Young Patients With Advanced Solid TumorsChildhood Central Nervous System ChoriocarcinomaChildhood Central Nervous System Embryonal TumorChildhood Central Nervous System Germ Cell TumorChildhood Central Nervous System GerminomaChildhood Central Nervous System Mixed Germ Cell TumorChildhood Central Nervous System TeratomaChildhood Central Nervous System Yolk Sac TumorRecurrent Childhood Brain Stem GliomaRecurrent Childhood Central Nervous System Embryonal TumorUnspecified Childhood Solid Tumor, Protocol SpecificNCT00281944National Cancer Institute (NCI)42
Completed
Phase 2
The Efficacy of Oxaliplatin Plus S-1 for Treatment of Gastric CancerStomach NeoplasmsNCT01531452Chinese Academy of Medical Sciences43
Unknown
Phase 1
Preoperative S-1/OHP With Radiation Therapy for Low-lying Rectal Carcinoma in Neo-adjuvant SettingRectal CarcinomaNCT01227239Japan Clinical Cancer Research Organization45
Completed
Phase 2
Oxaliplatin-Based Chemotherapy and Chemoradiotherapy or Chemoradiotherapy in Esophageal or Gastroesophageal CarcinomaEsophageal CancerGastroesophageal CancerNCT00525915M.D. Anderson Cancer Center126