The Effect of Relaxation Breathing Exercise on Chemotherapy Induced Nausea and Vomiting in Patients With Hematological Malignancies
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 68
- 试验地点
- 1
- 主要终点
- Change from the start of the chemotherapy in the frequency and severity of nasea, vomiting and retching at 6 days.
研究概览
简要总结
The Effect of Relaxation Breathing Exercise on Chemotherapy Induced Nausea and Vomiting in Patients With Hematological Malignancies ABSTRACT
Background:
Chemotherapy is widely used in the treatment of hematological malignancies despite it has important and difficult side effects in patients. Chemotherapy induced nausea and vomiting are among the most common side effects in patients and antiemetic drugs may not be always curative.
Purpose:
This research aimed to determine the effectiveness of relaxation breathing exercise on managing chemotherapy induced nausea and vomiting in patients with hematological malignancies undergoing chemotherapy.
Method:
A randomized controlled trial design was conducted with a total of selected sixty eight patients with hematological malignancies (34 intervention and 34 control participants) undergoing chemotherapy hospitalized in the hematology clinic of a Training and Research Hospital. The intervention group implemented relaxation breathing exercise three times a day with a standard treatment protocol and the control group only received routine drug treatment for chemotherapy induced nausea and vomiting. Nausea and vomiting were assessed by filling Rhodes Index of Nausea Vomiting and Retching (RINVR) for the first six days after the start of the chemotherapy.
Results:
Data collection process ended. Data analysis process is in progress.
Conclusion:
In this study the effectiveness of relaxation breathing exercise on chemotherapy related nausea and vomiting will be examined in patients with hematological malignancies.
Keywords: Relaxation breathing exercise; Hematological malignancies; Chemotherapy; Nausea and vomiting
详细描述
The research was conducted in the hematology clinics of a university training and research hospital in Istanbul, Turkey. Hospitalized patients with hematological malignancies who underwent chemotherapy were included in the research. Hematology patients apply to the hematology polyclinics in the hospital and then patients who are diagnosed with hematological malignancies such as leukemia, lymphoma or multiple myelome and will receive chemotherapy are hospitalized. The researcher planned to help patients to cope with nausea and vomiting while they were receiving chemotherapy in this study. Before the chemotherapy had been started, the relaxation breathing exercise training was provided to the hospitalized patients in their rooms who agreed to participate in the study. After training a guidebook about relaxation breathing exercise was given to the patients so that they would not forget how to implement the intervention
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged 18 years or over with hematological malignancies
- •Undergoing chemotherapy
- •Not having any communication problems (able to read, write and speak Turkish.
排除标准
- •Having psychiatric and mental problems
- •Receiving radiotherapy concurrent with chemotherapy, 3) Having respiratory distress
- •Having central nervous system involvement
- •Having Grade 3 or Grade 4 nausea and vomiting.
研究组 & 干预措施
Relaxation breathing exercise intervention group
干预措施: Relaxation breathing exercise (Behavioral)
Control group
干预措施: Control group (Behavioral)
结局指标
主要结局
Change from the start of the chemotherapy in the frequency and severity of nasea, vomiting and retching at 6 days.
时间窗: From enrollment to the end of intervention at 6 days
Zero is equivalent to no nausea, no vomiting and no retching and 4 indicates the worst and unbearable nausea, vomiting and retching
次要结局
未报告次要终点
研究者
Pınar Eksi
Principal investigator
Marmara University