Comparison of two different doses of Dexmedetomidine (a drug used for extending the duration of action of Spinal anaesthesia) with the routinely used drug (Bupivacaine) in Spinal Anaesthesia in patients undergoing surgeries below the umbilicus (navel region).
Not Applicable
- Conditions
- Health Condition 1: K409- Unilateral inguinal hernia, without obstruction or gangrene
- Registration Number
- CTRI/2023/10/058817
- Lead Sponsor
- Dr Gayathri Subhash Banasode
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
120 adult patients between the age group of 20-65yrs of physical status American Society of Anesthesiologists Physical Status I and II who undergo infra umbilical surgeries e.g.: Inguinal hernia repair surgeries, varicose vein surgeries, lower limb surgeries, etc.
Exclusion Criteria
Uncooperative patients, patients with uncontrolled hypertension, and diabetes, patients with allergy to the study drugs, patients on antiarrhythmics, beta-blockers, anticoagulants, ACE inhibitors, pregnant women, body weight >120kg, Heart Rate < 60 beats per minute and patients having a condition which is a contraindication to spinal anaesthesia such as patient refusal, infection at the site of injection, coagulopathy, increased intracranial pressure.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the pain after two different doses of dexmedetomidine 3µg and 5µg, as an additive to hyperbaric bupivacaine 0.5% via intrathecal route (Spinal).Timepoint: Baseline, 1st hour,2nd hour,4th hour and 6th hour.
- Secondary Outcome Measures
Name Time Method Onset and duration of sensory and motor block, hemodynamic effects, duration of analgesia, and occurrence of side effects.Timepoint: 6 hours