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Clinical Trials/NCT05643144
NCT05643144
Recruiting
N/A

Enhancing Shared Decision-making to Prompt and Guide Individualized Care for People With Alzheimer's Disease and Diabetes

Indiana University1 site in 1 country62 target enrollmentJune 7, 2023

Overview

Phase
N/A
Intervention
Not specified
Conditions
Diabetes
Sponsor
Indiana University
Enrollment
62
Locations
1
Primary Endpoint
Level of Situation Awareness (Aim 2)
Status
Recruiting
Last Updated
10 months ago

Overview

Brief Summary

Aim 1: Characterize shared decision-making and unmet patient-caregiver dyads needs for patients with diabetes and Alzheimer's Disease and related dementias (ADRD) while using a continuous glucose monitoring (CGM) device.

Aim 2: Develop an interactive tool to enhance shared decision-making for diabetes management.

Detailed Description

Aim 1: Patient-caregiver dyads will participant in a semi-structured interview to establish a baseline. The dyad will receive standard diabetes educational materials along with a CGM training and instructions for device use. Patients will then wear the CGM device for 14 days. Three follow-up interviews will take place during the 14-day scanning period, as well as a debrief interview following the scanning period for assessment and technical support. Aim 2: Patient-caregiver dyads and clinicians will participate in a user-centered design session to guide the design of interactive information displays to improve the interpretability of CGM data.

Registry
clinicaltrials.gov
Start Date
June 7, 2023
End Date
August 17, 2026
Last Updated
10 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

April Savoy

Assistant Professor

Indiana University

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Level of Situation Awareness (Aim 2)

Time Frame: 1 day

Contextual Inquiries: With and without examples of information displays present, we will invite participants questions related to identifying and reading glucose values (e.g., identify glycemic targets), and articulate perceived important information at specific decision points.

Patient and Caregiver Unmet Needs (Aim 1)

Time Frame: 2 months

Semi-structured Interviews: Baseline interview questions will be framed by validated psychometric measurements of hypoglycemia unawareness, fear of hypoglycemia, ADRD quality of life, and DM distress. Observation interviews will be conducted to elicit patients' and caregivers' perceptions about hypoglycemia and describe their specific risks (e.g., nutrition, resources, stress, finances). Debrief interviews will review CGM data with participants and ask clarifying questions to elicit descriptions of their overall experiences.

Secondary Outcomes

  • Feasibility: Retention rate of participants (Aim 1)(1 year)
  • Feasibility: Percentage of patients recruited (Aim 1)(1 year)
  • Feasibility: CGM data completeness (Aim 1)(2 months)
  • Hypoglycemia: Percentage of time below range (Aim 1)(2 months)
  • Mean glucose (Aim 1)(2 months)
  • Severe Hypoglycemia: Percentage of time below range (Aim 1)(2 months)
  • Percentage of time in range (Aim 1)(2 months)
  • Glucose management indicator (Aim 1)(2 months)
  • Glucose variability (Aim 1)(2 months)

Study Sites (1)

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