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Clinical Trials/NCT00145132
NCT00145132
Completed
Phase 4

Serotonin and Dopamine Transporter (SERT, DAT) Availabilities as Assessed by b-CIT and SPECT, and Neurophysiological Measures of Central Serotonergic Activity in Patients With Depression Under Treatment With Escitalopram

Ludwig-Maximilians - University of Munich1 site in 1 country30 target enrollmentJune 2005
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ConditionsDepression

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Depression
Sponsor
Ludwig-Maximilians - University of Munich
Enrollment
30
Locations
1
Primary Endpoint
changes in β-CIT/neurophysiological measurements from baseline to week 4
Status
Completed
Last Updated
15 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

Aim of this project is to investigate the effects of escitalopram on monoamine transporter (SERT, DAT) availabilities as assessed by b-CIT and SPECT, and on neurophysiological parameters such as the loudness dependence of auditory evoked potentials (LDAEP) in patients with depression.

Registry
clinicaltrials.gov
Start Date
June 2005
End Date
December 2009
Last Updated
15 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • •Psychiatric in or outpatients with acute depressive episode
  • •Indication for pharmacological treatment

Exclusion Criteria

  • •Acute suicidality
  • •Neurological or severe somatic disorders
  • •Occupational exposition to radiation \>15 mSv per year
  • •Women during pregnancy or lactation

Outcomes

Primary Outcomes

changes in β-CIT/neurophysiological measurements from baseline to week 4

Time Frame: two assessments, at baseline and week 4

Study Sites (1)

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