Serotonin and Dopamine Transporter (SERT, DAT) Availabilities as Assessed by b-CIT and SPECT, and Neurophysiological Measures of Central Serotonergic Activity in Patients With Depression Under Treatment With Escitalopram

Ludwig-Maximilians - University of Munich2 个研究点分布在 1 个国家目标入组 30 人开始时间: 2005年6月最近更新: 2010年6月2日

适应症

试验速览

阶段: 4 期
状态: 已完成
发起方: Ludwig-Maximilians - University of Munich
入组人数: 30
试验地点: 2
主要终点: changes in β-CIT/neurophysiological measurements from baseline to week 4

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Aim of this project is to investigate the effects of escitalopram on monoamine transporter (SERT, DAT) availabilities as assessed by b-CIT and SPECT, and on neurophysiological parameters such as the loudness dependence of auditory evoked potentials (LDAEP) in patients with depression.

研究设计

研究类型: Interventional
分配方式: Non Randomized
干预模型: Single Group
主要目的: Diagnostic
盲法: None

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Psychiatric in or outpatients with acute depressive episode
•Indication for pharmacological treatment

排除标准

•Acute suicidality
•Neurological or severe somatic disorders
•Occupational exposition to radiation >15 mSv per year
•Women during pregnancy or lactation

结局指标

主要结局

changes in β-CIT/neurophysiological measurements from baseline to week 4

时间窗: two assessments, at baseline and week 4

次要结局

未报告次要终点

研究者

发起方

Ludwig-Maximilians - University of Munich

申办方类型

Other

研究点 (2)

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