Integrative Medicine and Tai-chi in Clinical Status of Spinocerebellar Ataxia
Overview
- Phase
- Not Applicable
- Intervention
- Tai chi
- Conditions
- Spinocerebellar Ataxias
- Sponsor
- Changhua Christian Hospital
- Enrollment
- 21
- Primary Endpoint
- Scale for the Assessment and Rating of Ataxia(SARA)
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Spinocerebellar atrophy is the most common autosomal dominant inherited ataxia. There are over thirty subtypes, which characterize neurologic features differently. They all have obvious substantial cerebellar atrophies in image, and unstable gait、ataxia. In general a prevalence of about three cases per 100 000 people is assumed, but this may be an underestimate. Progressive neurologic degeneration, in about 10-20 years, will leads to disability or wheelchair-dependent. Accompanying with fatigue, downhill course of the disease often made patients depressive and hopeless. The recent review of researches concludes no effective therapy for the disease. The purpose of the investigator's study is to explore the Tai-chi exercise effect for spinocerebellar ataxia.
Investigators
Chiu Chung Min
Adjunct Physician
Changhua Christian Hospital
Eligibility Criteria
Inclusion Criteria
- •progressive ataxia accompanied with the observation of cerebellar atrophy on magnetic resonance or computed tomography images
- •SARA score of less than 20
Exclusion Criteria
- •Patients with complicated cerebellar disorders, such as multiple system atrophy, Parkinson-plus syndromes, secondary cerebellar degeneration from encephalitis, trauma, hypoxia, cerebrovascular diseases, and toxic- or drug-induced cerebellar degeneration
- •SARA score of larger than 20
Arms & Interventions
Tai chi
participants in this group accepted Tai chi exercise and conventional medicine.
Intervention: Tai chi
Tai chi
participants in this group accepted Tai chi exercise and conventional medicine.
Intervention: conventional medicine
controlled group
participants were not received Tai chi exercise, but only routine conventional medicine
Intervention: conventional medicine
Outcomes
Primary Outcomes
Scale for the Assessment and Rating of Ataxia(SARA)
Time Frame: assessed at baseline and 9 months, 9 months reported as Outcome Measure Data
SARA assesses eight aspects of cerebellar function: walking, sitting, standing, speaking, finger chasing, the nose-finger test, fast alternating hand movements, and the heel-shin slide. The eight categories accumulate score ranging from 0 (no ataxia) to 40 (most severe ataxia).Gait (0-8 points),Stance (0-6 points),Sitting (0-4 points),Speech disturbance (0-6 points),Finger chase (0-4 points),Nose-finger test (0-4 points),Fast alternating hand movement (0-4 points),Heel-shin slide (0-4 points)