Effect of post-operative chlorhexidine on complications and postoperative pain after surgical removal of lower impacted third molars: a randomized controlled trial

Phase 4

Completed

• Conditions: alveolitis; 10019190

• Registration Number: NL-OMON54943
• Lead Sponsor: Isala Klinieken

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 128

Inclusion Criteria

patients over 18 years of age referred for removal of a wisdom tooth in the
mandible. Patient has ASA I.

Exclusion Criteria

- Patient is younger than 18 years
- Patient has an ASA of II,III en IV
- Patient has only one maxillary third molar that needs to be extracted/removed
- Patient has an active pericoronitis
- Patient has trismus
- Patient has chronic pain
- Patient is pregnant
- Patient has a known allergy for ibuprofen of other NSAID*s
- Patient has a known allergy for articaine of epinefrine
- Patient has a known allergy for gentamicin
- Intra-operative compliations for example excesive bleeding

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Does rinsing with chlorhexidine after lower third molar removal effect the<br /><br>postoperative complications?</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>• Does rinsing postoperative with chlorhexidine lower the postoperative pain<br /><br>intensity, measured with the VAS scale, after surgical removal of impacted<br /><br>lower third molars<br /><br>• Does rinsing postoperative with chlorhexidine lower the need for analgesics<br /><br>postoperative?<br /><br>• Does rinsing postoperative with chlorhexidine reduces the number of<br /><br>out-patient contacts?<br /><br>• Does rinsing postoperative with chlorhexidine reduces / affect the number of<br /><br>days of leave from work or study?</p><br>