NCT00711737已完成不适用
Open-label Study of the Changes in Metabolic Parameters in Patients Treated With Escitalopram for Six Months
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 27
- 试验地点
- 1
研究概览
简要总结
The purpose of this study is to explore the changes in metabolic parameters in patients treated with escitalopram for six months for major depression, generalized anxiety disorder or panic disorder, with or without agoraphobia.
详细描述
This is an open-label study, with 4 scheduled visits. Recruitment of 100 subjects. Assessments include demographics, diagnosis, smoking frequency, Clinical Global Scale (CGI-S), weight, height,blood pressure, waist and hip circumference and fasting blood glucose and lipd profile.
Statistical analysis will be exploratory and mainly descriptive.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Give informed consent
- •Requires pharmacological treatment with escitalopram for major depression, generalized anxiety disorder or panic disorder
- •Aged 21 years old and above
- •Able to comprehend and comply with protocol
- •Not pregnant and if of child-bearing age, using adequate methods of contraception
排除标准
- •Currently taking or has taken in previous 3 months, any other antidepressants, antipsychotics, mood stabilizers, weight loss or lipid-profile modifying drugs
- •Contraindications to escitalopram
- •Unstable medical illness and/or is already under treatment of diabetes, hypertension, dyslipidemia, ischemic heart disease
- •History of non-response to escitalopram
- •Meets IDF definition of metabolic syndrome
- •Significant risk of suicide
- •Primary diagnosis or comorbid diagnosis of psychotic disorder, bipolar disorder, substance dependence and/or dementia
研究者
研究点 (1)
Loading locations...
相似试验
已完成
1 期
Open Label Study for the Functional Characterization of Drug Metabolism and TransportGenotype-related Drug MetabolismNCT01788254Matthias Schwab144
已完成
不适用
Plasma-Induced Changes in the Metabolome Following Polyphenol ConsumptionProcesses, MetabolicNCT06144489Northumbria University12
已完成
不适用
Metabolic Effects of Treatment in Intermediate and High-Risk Prostate CancerProstate CancerNCT01599182University of Waterloo9
已完成
不适用
Metabolomics and Bariatric Surgery in Patients With Metabolically Unhealthy ObesityBariatric Surgery CandidateObesity, MorbidObesity, Metabolically BenignNCT06297928Parc de Salut Mar145
已完成
不适用
Biomarkers of Prednisolone Treatment (P05888)Glucose IntoleranceInsulin ResistanceHyperglycemiaNCT00971724Merck Sharp & Dohme LLC72