Effect of everyother day dosing regimen of latanoprost on intraocular pressure
Not Applicable
- Conditions
- Glaucoma.Ocular Hypertension,primary open angle glaucomaH40.0 , H4
- Registration Number
- IRCT201102265905N1
- Lead Sponsor
- Eye research center,Rassoul Akram Hospital, Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
The inclusion criteria are: Age =30 years, IOP =22 and =32 mmHg without any IOP lowering medication, cup to disc ratio =0.6, mean deviation of = -6 decibel in perimetry and open angles on gonioscopy. Patients with a history of prior ocular surgery, uveitis, herpetic keratitis, and allergy to latanoprost are excluded
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Intraocular pressure (IOP). Timepoint: 24 hours before instillation of latanoprost, baseline IOP was measured 3 times ,at 9AM,4PM,and 9PM and again after one and two months of drug usage,based on assigned protocol of drug instillation,were measured at the same time points. Method of measurement: Calibrated Goldmann applanation tonometer.
- Secondary Outcome Measures
Name Time Method Side effects related to drug. Timepoint: At each time visit after instillation of drug ,during 2-month period of study. Method of measurement: Anterior segment exam by slit lamp biomicroscopy,posterior segment exam by funduscopy lenses, visual acuity test by Snellen chart and patients own description of side effects like significant Itching,redness and burning sensation.