nderstanding the neural correlates of music and rhythm perception and the effect of Indian music and rhythm based cognitive remediation in Parkinsonâ??s disease

Wellcome Trust India Alliance DBT Intermediate CPHI Fellowship0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•For PD group
•1.Diagnosis of PD according to UK Brain Bank diagnostic criteria.
•2.Patients from both gender
•3.Age range 40 to 65 years.
•4.Right Handedness- determined by Edinburgh Handedness Inventory39
•5.With formal education of 7 years with fluency in Hindi , English or Kannada
•6.Patients with Hoehn and Yahr stage40 1 to 2.5.
•7.Normal or corrected vision and hearing.
•8.Patients who are adhering to medication /pharmacological treatment and those who have been on stable medication 2-month before recruitment.
•For Healty Control group (HC) group
•1.Right Handedness- determined by Edinburgh Handedness Inventory39
•2.HMSE score (score 24 or above)
•3.Age range â?? 40 to 65 years
•4.Both gender
•5.Adequate hearing and visual ability/ corrected vision and audition
•6.With formal education of 7 years with fluency in Hindi, English or Kannada and Right handedness.
•7.Fluent in speaking in English/Hindi/Kannada

•For PD group
•1.Cognitive impairment assessed by Hindi Mental status examination41 (HMSE score less than 24 )
•2.Patient undergoing or those who have undergone any other form of cognitive remediation or any music based therapy in the last 6-months.
•3.Any other psychiatric and neurological conditions other than PD.
•4.Neurologic or medical disorders interfering with gait or cognition such as previous stroke, head injury, brain tumour, rheumatologic or orthopaedic disorder etc
•5.Patients with severe sensory deficits (visual /auditory) which will affect participation in intervention study.
•6.Patients with severe level of depression or anxiety as assessed by HADS 42 or clinically evaluated psychotic - severe enough to hinder their participation in intervention as assessed by clinical interview with patient and care giver.
•7.Any contraindications for undergoing magnetic resonance imaging
•For HC group
•1.Formal training more than two years in any form of music
•2.History of any Neurological/Psychiatric/Neurosurgical condition. Score of 12 or more Kesslerâ??s 6 Screening Scale (K6)43

发起方

Wellcome Trust India Alliance DBT Intermediate CPHI Fellowship