Basic research for sepsis with gastrointestinal dysfunction by internal and external treatment therapy
- Conditions
- Sepsis
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1. ICU/EICU stay for more than 7 days;
2. Age 18-85 years old;
3. Those who meet the diagnostic criteria for sepsis;
4. Those who meet the diagnostic criteria for gastrointestinal dysfunction;
5. Those who meet the gastrointestinal dysfunction score = 1;
6. Those who meet the APACHE II score = 15 points;
7. Those who voluntarily or family members agree and sign the informed consent form.
1. Those who do not have the conditions for enteral feeding;
2. Those who have gastrointestinal dysfunction caused by primary gastrointestinal diseases or trauma;
3. Those who are diagnosed with gastrointestinal malignant tumors or other advanced malignant tumors;
4. Those who do not have bladder Those with pressure measurement conditions (bladder injury or contracture, urethral stenosis or rupture, etc.);
5. Those who used glycerin enema, mosapride, lactulose and other drugs to improve gastrointestinal function within 1 week before the test;
6. Those suffering from mental disorders;
7. Those who are pregnant or breastfeeding;
8. Those who are participating in other clinical trials.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method APACHE II score;TCM symptom score;serum lymphokine;Gastrointestinal Dysfunction Score;Intestinal fatty aid binding protein;intra-abdominal pressure;Peripheral blood T lymphocyte subsets;
- Secondary Outcome Measures
Name Time Method