NCT00863135已完成不适用
Effect of Continuous Positive Airway Pressure (CPAP) Treatment on Blood Pressure in Patients With Sleep Apnea and Refractory Hypertension
Corporacion Parc Tauli2 个研究点 分布在 1 个国家目标入组 68 人开始时间: 2008年12月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 68
- 试验地点
- 2
- 主要终点
- 24 hours blood pressure monitoring
研究概览
简要总结
The purpose of this study is to determine the effects of CPAP treatment on blood pressure in patients with sleep apnea syndrome (SAS) and refractory arterial hypertension (RAH).
Also, some of the mechanisms mediating SAS and RAH (systemic inflammation, oxidative stress, sympathetic hyperactivity) will be analyzed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •refractory arterial hypertension and sleep apnea with apnea-hypopnea index over 15
排除标准
- •excessive sleepiness
- •professional drivers
- •secondary arterial hypertension
结局指标
主要结局
24 hours blood pressure monitoring
时间窗: basal and after three months of CPAP treatment
次要结局
- oxidative stress and inflammatory mediators(basal and after three months of CPAP treatment)
研究者
Jaume Almirall
Dr.
Corporacion Parc Tauli
研究点 (2)
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