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临床试验/NCT00302874
NCT00302874已完成不适用

In-Hospital Hyperglycemia: Effects of Treatment on Glycemic Control and Clinical Outcome

Hadassah Medical Organization2 个研究点 分布在 1 个国家目标入组 400 人开始时间: 2003年2月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
400
试验地点
2
主要终点
Mean blood glucose during hospitalization

研究概览

简要总结

To improve glycemic control of inpatients admitted to the internal medicine wards, the researchers generated a protocol based on intensive insulin treatment for use in all inpatients with hyperglycemia.

The researchers hypothesize that intensive insulin treatment will improve the glycemic control and the outcome of hospitalized patients.

Study Information:

  • All patients with a history of diabetes admitted to the internal medicine ward were enrolled in the study.
  • At baseline, demographic and clinical information were obtained, including information necessary to determine the severity of the illness. Venous capillary blood glucose levels were checked 4 times a day by glucometer.
  • During the pre-intervention period, patients were treated according to the common practice in the hospital without any intervention. The study team collected the baseline data on the glycemic control and treatment of patients admitted with hyperglycemia.
  • During the intervention period, the study team visited the ward daily and guided the medical staff as to the use of the treatment protocol.
  • During the post-intervention period, the study team collected the data without active intervention in the implementation of the protocol.
  • Data was collected on the mode of treatment and glycemic control of all hyperglycemic patients throughout the study. The incidence of hypoglycemia, complications (myocardial infarction, stroke, infections), mortality, transfer to intensive care unit (ICU), length of hospitalization, and disposition at discharge were noted.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
盲法
None

入排标准

性别
All
接受健康志愿者

入选标准

  • All patients admitted to the internal medicine ward with hyperglycemia

排除标准

  • Patients admitted due to hypoglycemia, hyperosmolar state, and ketoacidosis

结局指标

主要结局

Mean blood glucose during hospitalization

次要结局

  • Hypoglycemic events
  • Length of in-hospital stay
  • Infections
  • Complications (myocardial infarction, stroke)
  • Disposition at discharge (home, nursing home)

研究者

申办方类型
Other

研究点 (2)

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