EHR-integrated rUTI Texting Platform

Not Applicable

Recruiting

• Conditions: Recurrent Urinary Tract Infection
• Interventions: Other: Usual care; Device: EHR-integrated texting platform (Urotrust)

• Registration Number: NCT06035601
• Lead Sponsor: University of Pennsylvania

Brief Summary

The goal of this clinical trial is to compare a texting platform to usual care for managing recurrent urinary tract infections (UTI).

The main question it aims to answer is:

• can a texting platform that integrates symptom triage and prevention education reduce the rate of unnecessary antibiotics for recurrent UTIs as compared to usual care?

Participants enrolled onto the texting platform will:

• receive evidence-based clinical guidance for the management of symptoms of UTI and receive educational videos on how to prevent UTIs. An important secondary outcome is to determine if the texting platform improves self-efficacy for the management of recurrent UTI.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-09-06
• Study First Submitted QC: 2023-09-06
• Study First Posted: 2023-09-13
• Status Verified: 2024-03
• Study Start: 2024-03-07
• Last Update Submitted: 2024-03-15
• Last Update Posted: 2024-03-19
• Primary Completion: 2025-06-15
• Study Completion: 2026-06-15

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

1. Provision of signed and dated informed consent form
2. Stated willingness to comply with all study procedures and availability for the duration of the study
3. Females who currently meet the criteria for recurrent UTIs
4. Age 18 years or older
5. Owns a mobile device with text messaging capability
6. Ability to read and write English
7. Currently receiving care from a provider in Penn Urogynecology or Penn Urology

Exclusion criteria:

1. History of known multidrug resistant UTIs
2. History of interstitial cystitis/bladder pain syndrome or current diagnosis of chronic pelvic pain
3. On continuous suppressive antibiotics currently
4. Currently pregnant or within 6 weeks of pregnancy
5. Transplant patient on immunosuppressive medication currently
6. Practice of chronic self-catheterization

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Usual care	Usual care	Patients will receive usual care through their providers.
Electronic health record (EHR)-integrated texting platform	EHR-integrated texting platform (Urotrust)	Patients will be enrolled into a texting platform for the management of recurrent UTI.

Primary Outcome Measures

Name	Time	Method
Rate of unnecessary antibiotics	3 months	Antibiotics prescribed for patients with negative urine culture or for patients with asymptomatic bacteriuria (positive urine culture but no symptoms suggestive of UTI)

Secondary Outcome Measures

Name	Time	Method
Healthcare-related quality of life: Recurrent UTI Impact Questionnaire score	3 months	Recurrent UTI Impact Questionnaire score (score range 0-10 for each subscale with 0 indicating strongly disagree)
Antibiotic prescriptions	3 months	Number of antibiotic prescriptions given for UTI episodes
Patient self-efficacy	3 months	Stanford self-efficacy for managing chronic disease 6-item score (mean score range 1-10 with mean 1 indicating less self-efficacy)
Healthcare utilization	3 months	Combined number of phone calls, secure messages, telehealth, and/or in-person visits per UTI episode
Patient medication compliance	3 months	Medication Adherence Self-Report Inventory score (score range 0-100 with 0 indicating no medication usage)
Patient satisfaction: Patient Global Impression of Improvement score	3 months	Patient Global Impression of Improvement score (score range 1-7 with 1 indicating very much better)
Healthcare-related quality of life: EQ-5D-5L score	3 months	EQ-5D-5L score (score range 1-5 for each subscale with 1 indicating no problems)

Trial Locations

Locations (1)

University of Pennsylvania; 🇺🇸 Philadelphia, Pennsylvania, United States