Whole Body MRI Imaging in Multiple Myeloma at 3 Tesla MRI : Added Value of Diffusion Weighted Imaging

• Conditions: Multiple Myeloma

• Registration Number: NCT01780766
• Lead Sponsor: Universitaire Ziekenhuizen KU Leuven

Brief Summary

Whole body MRI with diffusion weighted imaging is a useful imaging tool

* staging and diagnosis

* therapy monitoring All patients will be scanned before and during treatment. The findings on diffusion weighted imaging will be correlated to the golden standard (computer tomography and MRI (T1 and STIR)).

Detailed Description

Not available

Study Timeline

• Study Start: 2008-09
• Status Verified: 2013-01
• Study First Submitted: 2013-01-26
• Study First Submitted QC: 2013-01-28
• Last Update Submitted: 2013-01-28
• Study First Posted: 2013-01-31
• Last Update Posted: 2013-01-31
• Primary Completion: 2013-03
• Study Completion: 2014-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Patients with clinical and laboratory findings, highly suggestive for multiple myeloma.

Exclusion Criteria

• All patients who are not allowed to be scanned on MRI (Pacemaker, implants ed.)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Validation	2 years	Validation of whole body MRI diffusion-weighted imaging in multiple myeloma at 3 Tesla MRI: correlation of the new MRI imaging technique (diffusion weighted imaging)to standard validated imaging technique (Computer Tomography and Magnetic Resonance Imaging)

Secondary Outcome Measures

Name	Time	Method
Therapy assessment	4 years	Whole body MRI with Diffusion weighted imaging is useful for treatment monitoring in multiple myeloma patients during and after therapy.; Measurement of apparent diffusion coefficient (ADC) and comparison of ADC before, during and after therapy. Correlation of ADC with clinical findings and standard MRI findings.

Trial Locations

Locations (1)

University Hospitals Leuven; 🇧🇪 Leuven, Belgium