Maternal Inflammatory Parameters Within Routine Treatment With Betamethasone
- Conditions
- Preterm Birth
- Registration Number
- NCT02993744
- Lead Sponsor
- Medical University of Vienna
- Brief Summary
It is the aim of this study to detect the effect of Betamethasone on the maternal inflammatory parameters C-reactive protein (CRP) and leukocytes of a pregnant woman under threat of preterm delivery, for example because of a cervical infection.
- Detailed Description
BACKGROUND
Cortisone influences the maternal number of leukocytes and CRP of a pregnant woman. Because of that, it is difficult to know if the medical treatment of an infection was successful and accordingly if the diagnosis was justified.
METHODS
In this study, the blood results of 75 pregnant women under threat of preterm delivery (week of gestation 23+0 to 34+6), treated with Betamethasone will be analysed. 65 pregnant women without complications serve as control group.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 140
- week of gestation 23+0 until 34+6
-
infectious diseases f.e. hepatitis B or C, HIV
-
diseases of the thyroid gland
75 Patients facing preterm labour 65 Patients acting as a control group, without preterm labor
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method CRP 48h The CRP values in mg/dL before and 48h after the first Betamethasone application
- Secondary Outcome Measures
Name Time Method Leucocytes 48h The Leucocyte values in G/L before and 48h after the first Betamethasone application
Trial Locations
- Locations (1)
General Hospital Vienna
🇦🇹Vienna, Austria