Assessment of Maternal Inflammatory Parameters Within Routine Treatment With Betamethasone Under Threat of Preterm Delivery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 140
- 试验地点
- 1
- 主要终点
- CRP
研究概览
简要总结
It is the aim of this study to detect the effect of Betamethasone on the maternal inflammatory parameters C-reactive protein (CRP) and leukocytes of a pregnant woman under threat of preterm delivery, for example because of a cervical infection.
详细描述
BACKGROUND
Cortisone influences the maternal number of leukocytes and CRP of a pregnant woman. Because of that, it is difficult to know if the medical treatment of an infection was successful and accordingly if the diagnosis was justified.
METHODS
In this study, the blood results of 75 pregnant women under threat of preterm delivery (week of gestation 23+0 to 34+6), treated with Betamethasone will be analysed. 65 pregnant women without complications serve as control group.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •week of gestation 23+0 until 34+6
排除标准
- •infectious diseases f.e. hepatitis B or C, HIV
- •diseases of the thyroid gland
- •75 Patients facing preterm labour 65 Patients acting as a control group, without preterm labor
结局指标
主要结局
CRP
时间窗: 48h
The CRP values in mg/dL before and 48h after the first Betamethasone application
次要结局
- Leucocytes(48h)
研究者
Kastanek Maria
Student
Medical University of Vienna