Social Influence on acute and chronic pain in women - an fMRI study
- Conditions
- chronic/recurrent pelvic pain, dysmenorrhea, endometriosisN94.4N94.5N80R10.2Primary dysmenorrhoeaSecondary dysmenorrhoeaEndometriosisN94.6Pelvic and perineal pain
- Registration Number
- DRKS00023753
- Lead Sponsor
- niversitätsklinikum Heidelberg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 75
• chronic/recurrent pelvic pain
• suspicion of endometriosis
• Patients must be able to specify a range of maximally 7 days with regard to their next menstrual onset.
• long-cycle treatment with oral contraceptives
• current or preceding neurological
• current psychotic disorder
• current psychopharmacological treatment
• psychoactive medication, preceding alcohol abuse or substance abuse
• chronic cardiovascular disease
• pacemaker or other inlying/ external medical devices
• metal implant or metal foreign objects
• current pregnancy or lactation
• current hormonal fertility treatment
• cancer of the breast, cervix or ovary
• other types of cancer
• acute infections
• pain disorders:
o migraine
o rheumatic diseases
o ulcerative colitis
o fibromyalgia
o Crohn´s disease
o irritable bowel syndrome
o others
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary goal of the study is to get a better understanding of the influence of stress on pain in chronic and/or recurrent visceral pain. We aim to investigate whether acute stress can affect the perception and processing of acute pain on subjective, neural, endocrine and physiological levels and systematically compare the underlying mechanism in patients and healthy controls.<br><br>Planned: N=60 patients and N=60 matched healthy controls
- Secondary Outcome Measures
Name Time Method Questionnaire and demographic data, such as age, will be analyzed as covariates.