MedPath

Fimasartan Blood Pressure Lowering After Acute Stroke

Completed
Conditions
Ischemic Stroke
Hypertension
Transient Ischemic Attack
Registration Number
NCT03231293
Lead Sponsor
Boryung Pharmaceutical Co., Ltd
Brief Summary

This study evaluates the effectiveness of fimasartan-based antihypertensive treatment and prognosis in post-acute phase of ischemic stroke or transient ischemic attack patients. All participants will receive fimasartan, and the investigators will follow them up for 6 months.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1035
Inclusion Criteria
  • Ischemic stroke or transient ischemic attack occurs after 7 days to 3 months.
  • Mean blood pressure measured 3 times at the first visit (Visit 1) should be over 140 mmHg for systolic blood pressure or 90 mmHg for diastolic blood pressure
  • Suitable for administration of fimasartan
  • The life expectancy should be over 6 months.
Exclusion Criteria
  • Patients already treated with antihypertensive medications
  • Hemorrhagic stroke patients

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
BP24 weeks

Blood pressure control rate(\<140/90 mmHg)

Secondary Outcome Measures
NameTimeMethod
Fimasartan-based treatment24 weeks

Fimasartan-based treatment modalities

Fimasartan starting point24 weeks

Fimasartan starting point after stroke

Mortality rates of any cause24 weeks

Mortality rates of any cause

Adverse events24 weeks

Adverse events related to antihypertensive treatments

mRS4, 12, 24 weeks

mRS changes

Cardiovascular events24 weeks

Incidence of cardiovascular events

Mortality rates from cardiovascular disease24 weeks

Mortality rates from cardiovascular disease

Stroke recurrence24 weeks

Rate of stroke recurrence

BP4, 12, 24 weeks

Blood pressure changes

Trial Locations

Locations (27)

Korea University Ansan Hospital

🇰🇷

Ansan, Korea, Republic of

Hallym University Medical Center

🇰🇷

Anyang, Korea, Republic of

Dong-A University Hospital

🇰🇷

Busan, Korea, Republic of

Inje University Busan Paik Hospital

🇰🇷

Busan, Korea, Republic of

Pusan National University Hospital

🇰🇷

Busan, Korea, Republic of

Keimyung University Dongsan Medical Center

🇰🇷

Daegu, Korea, Republic of

Kyungpook National University Hospital

🇰🇷

Daegu, Korea, Republic of

Daejeon Eulji Medical Center

🇰🇷

Daejeon, Korea, Republic of

Inje University Ilsan Paik Hospital

🇰🇷

Goyang, Korea, Republic of

Myongji Hospital

🇰🇷

Goyang, Korea, Republic of

Scroll for more (17 remaining)
Korea University Ansan Hospital
🇰🇷Ansan, Korea, Republic of

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.