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临床试验/NCT03729583
NCT03729583已完成不适用

The Effects of Breathing Retraining on Dyspnoea Measures and the Six-Minute Walking Distance in Patients With Interstitial Lung Diseases

University of Malta1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2017年7月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
30
试验地点
1
主要终点
6 minute walk test

研究概览

简要总结

Breathing retraining has been reported to lead to improvements in dyspnoea and walking distance in chronic obstructive pulmonary disease (COPD) patients. Evidence regarding the effects of such an intervention in ILD patients is though lacking. In view of this, the aims of such a study were to identify whether breathing retraining led to better management of dyspnoea and improved walking distance in ILD patients.

详细描述

One of the commonest symptoms experienced in patients with a diagnosis of interstitial lung disease (ILD) is shortness of breath, a symptom which greatly affects their abilities to carry out activities of daily living. Breathing retraining has been reported to lead to improvements in dyspnoea and walking distance in chronic obstructive pulmonary disease (COPD) patients. Evidence regarding the effects of such an intervention in ILD patients is though lacking. In view of this, the aims of such a study were to identify whether breathing retraining led to better management of dyspnoea and improved walking distance in ILD patients. Twenty Seven ILD patients were randomly distributed to either the control group (n=15) which received a 12-week Pulmonary Rehabilitation (PR) programme without breathing retraining or the active group (n=12) which received a 12-week PR programme with breathing retraining. All patients had both the 6-minute walk test and their level of breathlessness assessed using the Dyspnoea Borg scale assessed at baseline and at 4 weekly intervals for a 12-week period throughout the programme.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Investigator)

入排标准

性别
All
接受健康志愿者

入选标准

  • Patients with a confirmed diagnosis of ILD and who were referred for PR

排除标准

  • Patients who had musculoskeletal or neurological conditions affecting the outcome measures
  • Patients who required oxygen therapy and did not accept administration
  • Patients with unstable cardiovascular conditions
  • Patients who were not willing to participate

研究组 & 干预措施

Control group

Active Comparator

The control group consisted of 15 patients with a diagnosis of ILD. They received a 12-week Pulmonary Rehabilitation (PR) programme without breathing retraining All patients were medically stable and referred by their caring respiratory consultant

干预措施: Pulmonary Rehabilitation (Behavioral)

Active group

Experimental

The active group consisted of 15 patients with a diagnosis of ILD. They received a 12-week Pulmonary Rehabilitation (PR) programme with breathing retraining exercises. All patients were medically stable and referred by their caring respiratory consultant

干预措施: Pulmonary Rehabilitation (Behavioral)

结局指标

主要结局

6 minute walk test

时间窗: Change in walking distance from baseline to 12weeks

A walk test to examine exercise endurance

次要结局

  • Dyspnoea score(Change in dyspnoea measures from baseline to 12weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Melanie Axiak

Principal Investigator

University of Malta

研究点 (1)

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