EUCTR2008-002578-36-FR
Active, not recruiting
Phase 1
Etude d’efficacité et d’acceptabilité d’un traitement cholinergique dans l’apathie parkinsonienne Cholinergic treatment in Parkinsonian Apathy: ChoPA - I” - ChoPA-I
CHRU de LILLE0 sites29 target enrollmentJuly 21, 2008
DrugsExelon patch
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- CHRU de LILLE
- Enrollment
- 29
- Status
- Active, not recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Parkinson dieases since 5 years
- •MMSE score \=27
- •Matis score \=130
- •No dementia and depression (defined by the DSM\-IV)
- •MADRS score \< 18
- •IF subthalamic stimulation there are more critria
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range
Exclusion Criteria
- •more 80 years old
- •dopaminergic treatment
- •Treatment by High frequency stimulation of subthalamic nuclei
- •resting tremor very severe and uncontrolled
- •psychosis dopaminergic
- •Hypersensitivity to cholinesterase ihnibitor
- •Important cardivascular disorder
- •hepatic insufficiency
- •Evolutionary gastro\-duodenal ulcer
- •undernutrited
Outcomes
Primary Outcomes
Not specified
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