跳至主要内容
临床试验/CTRI/2025/12/099716
CTRI/2025/12/099716尚未招募不适用

Efficacy of erector spinae plane block versus retrolaminar block for perioperative analgesia following posterior dorso-lumbar spine instrumentation surgery

未提供1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2026年3月2日最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
尚未招募
入组人数
40
试验地点
1
主要终点
VAS score postoperatively upto 24 hours

研究概览

简要总结

Spine instrumentation surgeries involve extensive amount of tissue and bone trauma thus resulting in significant perioperative pain. Effective analgesia involves a multimodal approach combining systemic medications, regional nerve blocks, and patient controlled analgesia. Recently, regional analgesia techniques, such as the erector spinae plane block (ESPB), retrolaminar block (RLB) and thoracolumbar interfascial plane (TLIP) block, are being used. In this study, we will compare the efficacy of ultrasound guided ESPB and RLB in decreasing perioperative pain, the requirement of systemic analgesics and maintaining haemodynamic stability in dorsolumbar spine instrumentation surgeries. This will be a single blinded randomised controlled trial. After randomisation into two groups, we will administer either of ESPB or RLB with 19 ml 0f 0.25 % bupivacaine and 1 ml of dexamethasone bilaterally at a single targeted level approximately half an hour before surgery. We will record haemodynamics at various time points, and postoperative pain scores upto 24 hours. We will also document the requirement of systemic rescue analgesics postoperatively.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant Blinded

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • •Age 18 – 65 years of age
  • •Either gender
  • •ASA status I-II
  • •Patients undergoing thoracolumbar spine instrumentation surgeries
  • •Patients getting extubated at the end of the surgery
  • •Patients with intact mentation and speech.

排除标准

  • •Surgery duration exceeding 3 hours
  • •Patient having any coagulopathy
  • •Patient having scar or infection at injection site
  • •Patient having any psychiatric disorder, severe cardiac, pulmonary, hepatic or renal insufficiency
  • •History of preoperative chronic opioid use, long term drinking or psychotropic drug use
  • •Pregnancy and lactation
  • •History of allergy or anaphylaxis to any local anesthetic
  • •Spine instrumentation not more than 3 vertebral levels
  • •Intraoperative alteration of surgery
  • •Patients who will withdraw for any reason.

结局指标

主要结局

VAS score postoperatively upto 24 hours

时间窗: upto 24 hours after extubation

次要结局

  • (a) first time to postoperative systemic rescue analgesic((b) perioperative hemodynamics upto 24 hours postoperatively)

研究者

发起方
未提供
责任方
Principal Investigator
主要研究者

Dr Soumya Chakrabarti

IPGMER Kolkata

研究点 (1)

Loading locations...

相似试验