Efficacy of erector spinae plane block versus retrolaminar block for perioperative analgesia following posterior dorso-lumbar spine instrumentation surgery
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- VAS score postoperatively upto 24 hours
研究概览
简要总结
Spine instrumentation surgeries involve extensive amount of tissue and bone trauma thus resulting in significant perioperative pain. Effective analgesia involves a multimodal approach combining systemic medications, regional nerve blocks, and patient controlled analgesia. Recently, regional analgesia techniques, such as the erector spinae plane block (ESPB), retrolaminar block (RLB) and thoracolumbar interfascial plane (TLIP) block, are being used. In this study, we will compare the efficacy of ultrasound guided ESPB and RLB in decreasing perioperative pain, the requirement of systemic analgesics and maintaining haemodynamic stability in dorsolumbar spine instrumentation surgeries. This will be a single blinded randomised controlled trial. After randomisation into two groups, we will administer either of ESPB or RLB with 19 ml 0f 0.25 % bupivacaine and 1 ml of dexamethasone bilaterally at a single targeted level approximately half an hour before surgery. We will record haemodynamics at various time points, and postoperative pain scores upto 24 hours. We will also document the requirement of systemic rescue analgesics postoperatively.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)(—)
- 性别
- All
入选标准
- •Age 18 – 65 years of age
- •Either gender
- •ASA status I-II
- •Patients undergoing thoracolumbar spine instrumentation surgeries
- •Patients getting extubated at the end of the surgery
- •Patients with intact mentation and speech.
排除标准
- •Surgery duration exceeding 3 hours
- •Patient having any coagulopathy
- •Patient having scar or infection at injection site
- •Patient having any psychiatric disorder, severe cardiac, pulmonary, hepatic or renal insufficiency
- •History of preoperative chronic opioid use, long term drinking or psychotropic drug use
- •Pregnancy and lactation
- •History of allergy or anaphylaxis to any local anesthetic
- •Spine instrumentation not more than 3 vertebral levels
- •Intraoperative alteration of surgery
- •Patients who will withdraw for any reason.
结局指标
主要结局
VAS score postoperatively upto 24 hours
时间窗: upto 24 hours after extubation
次要结局
- (a) first time to postoperative systemic rescue analgesic((b) perioperative hemodynamics upto 24 hours postoperatively)
研究者
Dr Soumya Chakrabarti
IPGMER Kolkata
