Pulmonary Rehabilitation in Patients With Fibrotic Interstitial Lung Disease

University of California, San Francisco1 site in 1 countryDecember 22, 2006

ConditionsFibrotic Interstitial Lung Disease

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Fibrotic Interstitial Lung Disease
Sponsor: University of California, San Francisco
Locations: 1
Status: Terminated
Last Updated: 18 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Our study aims to investigate the benefits of an outpatient pulmonary rehabilitation program in a population of subjects with fibrotic interstitial lung disease. Our hypothesis is that pulmonary rehabilitation will lead to improvements in quality of life, breathlessness, exercise capacity and pulmonary function in this patient population.

Registry

clinicaltrials.gov

Start Date

December 22, 2006

End Date

July 2007

Last Updated

18 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

University of California, San Francisco

Eligibility Criteria

Inclusion Criteria

•Restriction on pulmonary function testing (TLC \<80%, FEV1/FVC ratio \> predicted or DLCO \< 80%)
•Evidence of fibrosis on high resolution computed tomography of the chest.
•Fibrosis on surgical lung biopsy if performed
•Referral for pulmonary rehabilitation

Exclusion Criteria

•Participation in pulmonary rehabilitation in the past 24 months
•Inability to complete 6 minute walk test or study questionnaires
•Limitations other than dyspnea (e.g. arthritis) that affect ability to participate in pulmonary rehabilitation
•Baseline 6 minute walk distance \> 400 meters
•Planned change in medication treatment for lung disease during the course of pulmonary rehabilitation
•Ejection fraction known to be \< 25%
•Contraindications to pulmonary rehabilitation (clinically unstable, uncontrolled arrhythmia or hypertension, symptomatic or uncontrolled hypotension with systolic blood pressure of \< 95, active angina, unexplained syncope or worsening dizziness, limiting orthopedic or neurological disorders, psychiatric impairment that inhibits cooperation in the program)
•FEV1/FVC \< 65%
•Unable to provide informed consent