4D Flow Quantification with MRI

• Conditions: Verworven structuele hartaandoeningen; structural heart disease; Heart diseases; 10010394

• Registration Number: NL-OMON41077
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

•Men and women aged >18 years
Children between 8-12 years.
Children between 12-18 years.
• Clinical referral for CMR in the absence of any contraindication to MRI; Intra-cardiac flow measurements are part of the CMR indication.
• Signed informed consent.

Exclusion Criteria

Any contraindication to an MRI scan or gadolinium contrast media (renal failure, allergy) per the policy of Erasmus University Medical Center Rotterdam.
• Inability or unwillingness to provide informed consent.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Intracardiac blood flow and flow velocity measured by 4D MR and compared with<br /><br>2D MR.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>• Intracardiac pressures as assessed by 4D MR, 2D MR, invasive catheterization<br /><br>and echocardiography.<br /><br>• Intracardiac shunting as assessed by 4D MR, 2D MR, invasive catheterization<br /><br>and echocardiography. </p><br>