Cerebral Antibiotics Distribution After Acute Brain Injury

Phase 1

Completed

• Conditions: Bacterial Infection; Brain Injury
• Interventions: Drug: Fosfocine; Drug: Metronidazole; Drug: Ciprofloxacin; Drug: cefotaxime

• Registration Number: NCT01059890
• Lead Sponsor: Poitiers University Hospital

Brief Summary

The aim of the study is to explore the distribution of antibiotics in the brain after an acute brain injury because brain infections treatment is still an health care problem.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-09
• Study First Submitted: 2010-01-29
• Study First Submitted QC: 2010-01-29
• Study First Posted: 2010-02-01
• Primary Completion: 2013-06
• Status Verified: 2016-10
• Last Update Submitted: 2016-10-10
• Last Update Posted: 2016-10-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

• Acute brain injury
• Patient who receive an antibiotic for an infection or prophylaxy
• Glasgow coma score < 8

Exclusion Criteria

• Age < 18 years old
• Pregnant woman
• HCV, HIV, HBV infection

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Fosfocine	Fosfocine	-
Metrodinazole	Metronidazole	-
Ciprofloxacine	Ciprofloxacin	-
Cefotaxime	cefotaxime	-

Trial Locations

Locations (1)

Poitiers University Hospital - 2 rue de la Milétrie - Réanimation chirugicale; 🇫🇷 Poitiers, France