europhysiological analysis of ADHD: an exploratory neuroimaging study using functional near-infrared spectroscopy (fNIRS)
Not Applicable
Recruiting
- Conditions
- Attention deficit hyperactivity disorder
- Registration Number
- JPRN-UMIN000008831
- Lead Sponsor
- Department of Neurosurgery, Jichi Medical University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
(1) Subjects who are diagnosed with anxiety disorder (2) Subjects who are diagnosed with glaucoma (3) Subjects who are diagnosed with hyperthyroidism (4) Subjects who have angina, arrhythmia (5) Subjects who have allergies to MPH (6) Subjects who are diagnosed with tics or Tourette's syndrome, or have family history of Tourette's syndrome (7) Subjects who are diagnosed with severe depression (8) Subjects who are diagnosed with pheochromocytoma (9) Subjects who current or past use of monoamine oxidase inhibitor (MAOI
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method (1) fNIRS analysis Comparison of frontal activation (oxy-Hb, deoxy-Hb and total-Hb, measured by fNIRS) before and after an acute clinical dose of MPH or placebo (90 min after MPH administration) (2) Behavioral performance Comparison of reaction time and percentage of correct response on target detection task before and after the acute clinical dose of MPH or placebo (90 min after MPH administration)
- Secondary Outcome Measures
Name Time Method The response of continuous administration of MPH on ADHD rating scale and Questionnaire-Children with Difficulties