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Clinical Trials/NCT03456869
NCT03456869
Unknown
Not Applicable

The Application and Clinical Accuracy of Patient-specific Implants in Genioplasty

Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University1 site in 1 country30 target enrollmentNovember 1, 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Genioplasty
Sponsor
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Enrollment
30
Locations
1
Primary Endpoint
Positional differences of the chin between the plan and postoperative results
Last Updated
8 years ago

Overview

Brief Summary

The purpose of this study is to assess the accuracy and clinical validation of patient specific implants (PSI) technique for genioplasty.

Detailed Description

Chin plays an important role in the lower facial harmony and balance. With the advances in computer-aided surgical simulation (CASS) technology, surgeons are now able to simulate surgical procedures in the computer to achieve the best possible surgical plan. However, CAD/CAM surgical templates do not maximize the potential of CASS technique. Patient specific implants (PSI) has rapidly developed in cranio-maxillofacial surgery in the past few years. However, few studies have introduced PSI technique in osseous genioplasty. The purpose of this study is to assess the accuracy and clinical validation of patient specific implants (PSI) technique in genioplasty for positioning and fixation of the chin segment. Anticipated 30 patients with chin deformities are enrolled. Virtual planning is performed with the computer-aided surgical simulation method. The 3D printing titanium cutting guide and patient specific plate is involved in this PSI method. The cutting guide is designed to guide the osteotomy and screw holes drilling for the following patient specific plate. And the patient specific plate is used to simultaneously complete the reposition and fixation of the chin. The outcome is evaluated by comparing the plan with actual outcomes.

Registry
clinicaltrials.gov
Start Date
November 1, 2015
End Date
December 31, 2019
Last Updated
8 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Responsible Party
Principal Investigator
Principal Investigator

Xudong Wang

Acting chair of Department of Oral and Craniomaxillofacial Surgery

Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

Eligibility Criteria

Inclusion Criteria

  • patients who were scheduled to undergo genioplasty;
  • patients who were scheduled to undergo CT scan as a part of their diagnosis and treatment;
  • patients who agreed to participate in this study

Exclusion Criteria

  • craniofacial syndrome;
  • segmental osseous genioplasty;
  • previous osseous genioplasty;
  • previous mandibular trauma;
  • systemic disorders.

Outcomes

Primary Outcomes

Positional differences of the chin between the plan and postoperative results

Time Frame: 2 weeks after the operation

The coordinates of the centroid of three land points on the chin segment was used to calculate the position differences between the plan and postoperative results in X, Y and Z axis.

Orientation differences of the chin between the plan and postoperative results

Time Frame: 2 weeks after the operation

The coordinates of three independent points were used to define the orientation of the chin in 3D space. The orientation differences were calculated in pitch (the rotation around the X axis), roll (the rotation around the Y axis), and yaw (the rotation around the Z axis).

Secondary Outcomes

  • time consuming(3 days after the operation)
  • economic consuming(3 days after the operation)

Study Sites (1)

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