Prevention of NEphronic PErt in People With Type 2 DIABETIC Disease Followed in General Practice

University Hospital, Lille0 sites360 target enrollmentJuly 1, 2026

ConditionsRenal Insufficiency and Diabetes Mellitus

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Renal Insufficiency and Diabetes Mellitus
Sponsor: University Hospital, Lille
Enrollment: 360
Primary Endpoint: Change in annual glomerular filtration rate (GFR) slope
Status: Not yet recruiting
Last Updated: 4 months ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

This work will make it possible to identify the nephron loss of type 2 diabetic patients in the western region and to better define in general practice the impact of the elements put in place to reduce this loss and to raise awareness of the importance of these measures through training in comparison with a control group.

Registry

clinicaltrials.gov

Start Date

July 1, 2026

End Date

July 1, 2027

Last Updated

4 months ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

University Hospital, Lille

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Patient consulting his or her investigating general practitioner
•50 years old or more
•type 2 diabetic for more than 5 years, with a GFR lower than 90 ml/mn and higher than 45 ml/mn (stage 2 and 3a of renal failure) and a nephron loss calculated on the average of the two previous years, higher than 3 ml/mn/year
•a microalbuminuria \> 30 mg/gr of creatinuria.
•Having declared the investigator as the treating physician

Exclusion Criteria

•Patient under 50 years of age Patients who do not agree to the use of their data (refusal of consent) or are unable to give consent (dementia, other) Patients with other types of diabetes Patients with renal failure other than diabetic or hypertensive glomerulopathy Patients unable to give consent Patients who do not understand the French language Patients with less than 3 months of planned follow-up Patients with a barrier to follow-up Patients undergoing dialysis, transplantation

Outcomes

Primary Outcomes

Change in annual glomerular filtration rate (GFR) slope

Time Frame: Every 3 months during 2 years

the annual glomerular filtration rate (GFR) slope calculated as the difference between the estimated loss over the two years before inclusion (N-2) and the estimated annual loss over the follow-up years after inclusion.

Secondary Outcomes

Audit of clinical practices(before randomization, at 6 months and 24 months in the 2 groups)
change of Albuminuria(at baseline and every 3 months during the 2-year follow-up.)
Cumulative incidence of unscheduled hospitalizations for all reasons at 2 years from the start of care in the intervention group compared to the control group(At 2 years (the end of the study))