East-West Hepatocellular Carcinoma Study Group

Completed

• Conditions: Carcinoma, Hepatocellular

• Registration Number: NCT01237132
• Lead Sponsor: University of Milan

Brief Summary

The current treatment guidelines of hepatocellular carcinoma (HCC) of the American and European Associations for the Study of Liver Disease are based on the Barcelona-Clinic-Liver-Cancer classification (BCLC), which does not recommend surgery in patients with large, multinodular and macrovascular invasive disease. The aim of this study was to investigate the role of hepatic resection in a large retrospective multicentric cohort of patients resected for HCC regardless of the BCLC indications.

Detailed Description

Not available

Study Timeline

• Status Verified: 2009-12
• Study First Submitted: 2010-11-08
• Study First Submitted QC: 2010-11-08
• Last Update Submitted: 2010-11-08
• Study First Posted: 2010-11-09
• Last Update Posted: 2010-11-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• clinical diagnosis of hepatocellular carcinoma
• candidate to liver resection as a curative treatment

Exclusion Criteria

• uncertain diagnosis of hepatocellular carcinoma
• uncertain follow-up data

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Overall survival of resected patients for HCC		The primary endpoint of the study was the overall survival of patients resected for HCC in any stage of the BCLC classification.

Secondary Outcome Measures

Name	Time	Method
Disease-free survival of resected patients for HCC		The secondary endpoint was the disease-free survival of patients resected for HCC among the BCLC stages.