Is There a Benefit From Addition of Treadmill Walking to Diet Restriction in Psoriasis Women With PCOS?
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Cairo University
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Psoariasis area and severity index
Study Overview
Brief Summary
Women with psoriasis usually develop many complications including polysyctic ovarian syndrome (PCOS). Nowdays, diet restriction combimed with phsyical exercises may improve both problems
Detailed Description
Forty Women with psoriasis with PCOS will be enrolled to be catogrized to Group I or group II. Group I will enroll twenty females with PCOS and Psoriasis who will apply forty minutes walking on treadmill three times per week. Also Group I will follow low calorie diet and daily metformin for 12 weeks. Group II will will enroll twenty females with PCOS and Psoriasis who will follow low calorie diet and daily metformin for 12 weeks
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 35 Years to 45 Years (Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •obese (class I) women
- •chronic plaque psoriasis
- •polyscytic ovarian syndrome
Exclusion Criteria
- •cardiac dysfucntions
- •liver diseases
- •repsiratory disease
- •vascular diseases
Outcomes
Primary Outcomes
Psoariasis area and severity index
Time Frame: it will be measured after 12 weeks
is an index used to express the severity of psoriasis. It combines the severity (erythema, induration and desquamation) and percentage of affected area
Secondary Outcomes
- insuiln(It will be measured after 12 weeks)
- ratio of luteinizing hormone and follicle-stimulating hormone(It will be measured after 12 weeks)
- body mass index(It will be measured after 12 weeks)
- waist circumference(It will be measured after 12 weeks)
- waist hip ratio(It will be measured after 12 weeks)
- testesterone(it will be measured after 12 weeks)
- Dehydroepiandrosterone(It will be measured after 12 weeks)
- Dermatology life Quality Index(It will be measured after 12 weeks)
- HOMA-IR(It will be measured after 12 weeks)
- high density lipoprotein(It will be measured after 12 weeks)
- low density lipoprotein(It will be measured after 12 weeks)
- systolic blood pressure(It will be measured after 12 weeks)
- diatolic blood pressure(It will be measured after 12 weeks)
- total cholesterol(It will be measured after 12 weeks)
- fasting blood glucose(It will be measured after 12 weeks)
- triglycerides(It will be measured after 12 weeks)
Investigators
Ali Mohamed Ali ismail
lecturer of physical therapy for Cardiovascular, Respiratory disorder and Geriatrics, Faculty of Physical Therapy, Cairo University
Cairo University