Continuous Vs Intermittent Non Invasive Blood Pressure Monitoring in Preventing Post Operative Organ Failure
Overview
- Phase
- Not Applicable
- Intervention
- Continuous Non Invasive Blood Pressure Monitoring
- Conditions
- Blood Pressure Determination
- Sponsor
- University of Messina
- Enrollment
- 1267
- Locations
- 1
- Primary Endpoint
- Post operative myocardial injury
- Status
- Completed
- Last Updated
- last month
Overview
Brief Summary
Continuous non-invasive arterial pressure monitoring has the potential to decrease the duration of intraoperative hypotension and hypertension compared to conventional intermittent blood pressure monitoring. Chen et al. demonstrated using continuous non-invasive arterial pressure devices for every hour of surgery it is possible to identify an average of 14 minutes of potentially treatable hypotensive and hypertensive time(12). Whether the ability to detect more hypotension events by continuous non-invasive arterial pressure monitoring use can improve patient outcomes, is still an open research question
Investigators
Alberto Noto
Prof.
University of Messina
Eligibility Criteria
Inclusion Criteria
- •All adult (age ≥18 years) patients scheduled for elective non-cardiac surgery in participating centers
- •Surgical case planned with non invasive blood pressure monitoring according to local clinical practice or policies.
Exclusion Criteria
- •Missing of preoperative serum creatinine during 30 days prior surgery
- •Preoperative dialysis
- •Chronic kidney disease (eGFR \< 60ml/min Cockcroft-Gault equation)
- •Surgical procedure lasting less than 60 min
- •Planned use of permissive hypotension
- •Urological procedures (including nephrectomy and renal transplantation)
- •Refusal to give informed consent
Arms & Interventions
cNIBP
Continuous non invasive blood pressure monitor (Volume clamp)
Intervention: Continuous Non Invasive Blood Pressure Monitoring
iNIBP
Intermittent Non Invasive Blood Pressure (Brachial Cuff)
Intervention: Intermittent Non Invasive Blood Pressure Monitoring
Outcomes
Primary Outcomes
Post operative myocardial injury
Time Frame: 1 week
The primary outcome will be the proportions of myocardial injury (Definitions: elevation of serum Troponin T (TnT) \>= 30 ng/L in the first post-operative week)
Secondary Outcomes
- Post operative death(28 day after surgery)
- Events 30d post surgery(30 days after surgery)
- Events 90d post surgery(90 days after surgery)
- Post operative Acute kidney injury(1 week)