Evaluation of the Impact of Mobile Phone Messages on ART and PMTCT Adherence in Mozambique

Not Applicable

Completed

• Conditions: HIV-positive
• Interventions: Behavioral: SMS reminders

• Registration Number: NCT01910493
• Lead Sponsor: Absolute Return for Kids

Brief Summary

Mobile phone SMS are increasingly used to promote positive health behaviour with an aim to improve health outcomes. However, robust data on the efficacy of SMS on health seeking behaviour and patient outcomes in resource-limited settings is sparse. The SMSaude study aims to assess whether regular SMS-reminders improve retention on antiretroviral therapy (ART) and prevention of mother to child transmission of HIV (PMTCT) programmes in Mozambique.

Detailed Description

SMSaúde is a multisite randomised clinical trial of HIV-infected adults on ART and HIV-infected pregnant women in six clinics in Maputo Province, Mozambique. Eligibility criteria include: currently residing in the province; no plans to move for 12+ months; have own cell-phone; literate; 8-28 weeks pregnant (PMTCT cohort); on first line ART and on ART for \>15 days (ART cohort). Patients were interviewed for eligibility, and then randomized (1:1). SMS reminders are sent to the intervention group using software that picks up the patient's next appointment from the electronic patient database. Primary outcomes tested were improved retention in ART care and uptake of all PMTCT services.

Study Timeline

• Study Start: 2011-11
• Primary Completion: 2013-05
• Study Completion: 2013-06
• Status Verified: 2013-07
• Study First Submitted: 2013-07-25
• Study First Submitted QC: 2013-07-25
• Last Update Submitted: 2013-07-25
• Study First Posted: 2013-07-29
• Last Update Posted: 2013-07-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1352

Inclusion Criteria

• On ART for >15 days (for ART only)
• Live in province and plan to stay for 12+ months
• Have cell phone
• Literate

For PMTCT (in addition to above criteria):

• pregnant between 8-28 weeks

Exclusion Criteria

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
SMS reminders to PMTCT cohort	SMS reminders	experimental group
PMTCT no SMS reminders	SMS reminders	control group
SMS reminders to ART cohort	SMS reminders	experimental group
ART no SMS reminders	SMS reminders	control group

Primary Outcome Measures

Name	Time	Method
Retention in ART care	12 months

Secondary Outcome Measures

Name	Time	Method
Retention in PMTCT care	until 8 weeks post partum

Trial Locations

Locations (1)

6 Health Facilities; 🇲🇿 Matola, Xinavane, Machava and Namaacha, Maputo, Mozambique