NCT01691300已完成不适用
C11-Acetate PET/CT in Multiple Myeloma: Added Value to F18-Fluorodeoxyglucose PET/CT for Staging and Response Assessment
Chang Gung Memorial Hospital2 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2011年5月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Pretreatment lesion detection
研究概览
简要总结
Positron emission tomography combined with computed tomography using carbon-11 acetate (ACT PET/CT) may help detect lesions before treatment and evaluate response following therapy in patients with from multiple myeloma (MM). This study aimed to prospectively assess the clinical utility of ACT PET/CT in MM as compared to the commonly used F18-fluorodeoxyglucose(FDG).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •at least 20 years of age
- •previously untreated
- •complete pre-treatment clinical staging including bone marrow examination
- •written informed consent to participate in the study
排除标准
- •concurrent active malignant tumor(s)
- •pregnant or breast feeding women
- •non-compliant to PET/CT or to MRI
- •marked renal impairment (contraindicated for contrast-enhanced MRI)
结局指标
主要结局
Pretreatment lesion detection
时间窗: Within 2 weeks before initiation of therapy
Reference standards: bone marrow examination and whole-body dynamic contrast-enhanced MRI
次要结局
- Post-ASCT response assessment(Approximately 3 months after ASCT)
- Post-induction response assessment(Approximately 4 months after initiation of therapy depending on the regimen)
研究者
研究点 (2)
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