A clinical and radiographic evaluation of modified single buccal flap approach and its coronal respositioning with and without platelet rich fibrin (PRF) in periodontal intrabony defects- A double blind randomized controlled trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Probing depth, Clinical attachment level
研究概览
简要总结
periodontitis is an infectious disease that causes destruction of tooth attachment apparatus .untreated periodontitis results in progressive attachment loss that may eventually lead to early tooth loss. single buccal flap approach by Trombelli may be a suitable technique which is not investigated thoroughly in the treatment of periodontal intrabony defect. It is a minimally invasive surgical procedure designed for reconstructive therapy of interasseous defect.An intrabony defect is a periodontal defect is within the bone surrounded by one ,two ,or three bony walls or combination thereof. Ultimate goal of periodontal therapy is regeneration .periodontal regeneration refers reproduction or reconstruction of lost or injured part in which architecture and function of thee lost or injured tissues are completely restored.platelets can play a crucial role in periodontal in regeneration as they are the reservoir and of growth factors and cytokines which are the key factor for regeneration of bone and maturation of soft tissue. so the platelets rich fibrin will help in treatment of intrabony defect.
so the aim of present study is to evaluate the efficacy of single buccal flap approach and coronal repositioning with and without PRF in treatment of intrabony defect.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient diagnosed with localized or generalized chronic periodontitis as per American Academy of Periodontology International Workshop for Classifications of Periodontal Disease
- •Subjects having acceptable systemic health.
- •Intrabony defect in both maxillary or mandibular region.
- •Patients having at least one intrabony defect more than or equal to 3 mm along with attendant pocket depth more than or equal to 5mm.
- •Absence of overt clinical inflammation at the time of surgery.
- •Patient signing written informed consent.
排除标准
- •Medically compromised patients.
- •With unacceptable oral hygiene (Plaque index>2)
- •With any metabolic disease or endocrine disease having direct or indirect influence on Bone healing.
- •With any periapical pathology associated with endodontic infection in the region of Interest.
- •Patient on active orthodontic treatment.
- •Patient having >4 mm pocket in selected tooth on mid oral or palatal aspect, requiring Buccal as well as oral flap for access.
- •Pregnant and lactating women.
- •Presence of defective prosthesis in the area of interest.
- •Patient who are using drugs that may cause gingival enlargement, those allergic or sensitive to any medications that will be used in the study.
结局指标
主要结局
Probing depth, Clinical attachment level
时间窗: At 3 month and at 6 months
Radiographic bone fill
时间窗: At 3 month and at 6 months
次要结局
- Gingival marginal level, plaque index, gingival index(At 3month and at 6 months)