A Study to Compare and evaluate the effect of one sided gum surgery alone or in combination with Component of blood (PRF) in bony defects associated with gum disease.

Not yet recruiting

• Conditions: Chronic periodontitis, Periodontitis (osseous defects),

• Registration Number: CTRI/2019/10/021752
• Lead Sponsor: MIDSR Dental college

Brief Summary

periodontitis is an infectious disease that  causes destruction of tooth attachment apparatus .untreated periodontitis results in progressive attachment loss that may eventually lead to early tooth loss. single buccal flap approach by Trombelli may be a suitable technique which is not investigated thoroughly in the treatment of periodontal intrabony defect. It is a minimally invasive surgical procedure designed for reconstructive therapy of interasseous defect.An intrabony defect is a periodontal defect is  within the bone surrounded by one ,two ,or three bony walls or combination thereof. Ultimate goal of periodontal therapy is regeneration .periodontal regeneration refers reproduction or reconstruction of lost or injured part in which architecture and function of thee lost or injured tissues are completely restored.platelets can play a crucial role in periodontal in regeneration as they are the reservoir and of growth factors and cytokines which are the key factor for regeneration of bone and maturation of soft tissue. so the platelets rich fibrin will help in treatment of intrabony defect.

so the aim of present study is to evaluate the efficacy of single buccal flap approach and coronal repositioning with and without PRF in treatment of intrabony defect.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-10-12
• Last Update Posted: 2019-10-16

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

• Patient diagnosed with localized or generalized chronic periodontitis as per American Academy of Periodontology International Workshop for Classifications of Periodontal Disease 1999.
• Subjects having acceptable systemic health.
• Intrabony defect in both maxillary or mandibular region.
• Patients having at least one intrabony defect more than or equal to 3 mm along with attendant pocket depth more than or equal to 5mm.
• Absence of overt clinical inflammation at the time of surgery.
• Patient signing written informed consent.

Exclusion Criteria

• Medically compromised patients.
• With unacceptable oral hygiene (Plaque index>2) 3.
• With any metabolic disease or endocrine disease having direct or indirect influence on Bone healing.
• With any periapical pathology associated with endodontic infection in the region of Interest.
• Patient on active orthodontic treatment.
• Patient having >4 mm pocket in selected tooth on mid oral or palatal aspect, requiring Buccal as well as oral flap for access.
• Pregnant and lactating women.
• Presence of defective prosthesis in the area of interest.
• Patient who are using drugs that may cause gingival enlargement, those allergic or sensitive to any medications that will be used in the study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Probing depth, Clinical attachment level	At 3 month and at 6 months
Radiographic bone fill	At 3 month and at 6 months

Secondary Outcome Measures

Name	Time	Method
Gingival marginal level, plaque index, gingival index	At 3month and at 6 months

Trial Locations

Locations (1)

Department of Periodontology and Oral Implantology, MIDSR DENTAL COLLEGE; 🇮🇳 Latur, MAHARASHTRA, India

Department of Periodontology and Oral Implantology, MIDSR DENTAL COLLEGE

🇮🇳Latur, MAHARASHTRA, India

Saleem khan

Principal investigator

8421599981

salim0007dx15@gmail.com