Efficacy of an iron fortified complementary food in improving the nutritional status of children aged 6-18 months in the La Nkwantanang Municipality of the Greater Accra Regio

Not Applicable

• Conditions: Nutritional, Metabolic, Endocrine; Paediatrics

• Registration Number: PACTR201906885776793
• Lead Sponsor: estec Ltd

Brief Summary

There were no significant differences between groups in maternal/household characteristics or infant baseline anthropometry. At 6 months, adjusted mean±SE hemoglobin (Hb) change from baseline in control (CTL) and intervention (INT) groups was 1.16 ± 0.21 and 1.97 ± 0.19 g/dL, respectively (p < 0.01 for each); the increase over time was significantly larger in INT vs. CTL (0.68 ± 0.30 g/dL; p = 0.02). Similar results were found in unadjusted models. Hb levels declined slightly in both groups in the 2 month period after the intervention but remained higher in INT. Prevalence of anemia declined in both groups (CTL: 89.1% to 62.8%, INT: 84.1% to 42.8%); the magnitude of decrease was 57% greater in INT. There was no significant difference between groups in length gain (CTL: 6.24 ± 0.28, INT: 5.62 ± 0.27 cm; p = 0.21) or weight gain (CTL: 1.03 ± 0.24, INT: 1.31 ± 0.24 kg; p = 0.41). Iron-fortified infant cereal consumed for 6 months promoted greater reductions in iron-deficiency anemia in infants aged 6-18 months, which is a public health concern in Ghana and most developing countries.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-04-02
• Results First Posted: 2019-06-09
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Child age is between 6 and 18 months
Parents / caregivers live in the study area with no plans to move
Parents / caregivers able and willing to participate in the study

Exclusion Criteria

Child has an acute or chronic illness
Child is taking medication due to recent ailment
Child is allergic to wheat-based foods

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hemoglobin concentration

Secondary Outcome Measures

Name	Time	Method
Weight;Height;Mid-upper arm circumference;Dietary intake assessment