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Clinical Trials/NCT04889586
NCT04889586
Completed
Not Applicable

Hand Motor Recovery Using a EMG-biofeedback in Stroke Rehabilitation: a Cross-sectional Study

IRCCS San Camillo, Venezia, Italy1 site in 1 country100 target enrollmentJuly 25, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stroke
Sponsor
IRCCS San Camillo, Venezia, Italy
Enrollment
100
Locations
1
Primary Endpoint
Fugl-Meyer Upper Extremity (FMA-UE)
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

Recovery of upper limb and hand gestures is fundamental for autonomy restoration after stroke. Innovative technologies are a valid support for the delivery of rehabilitation treatments. Embedding surface electromyographic (sEMG) into wearable devices, allows the customisation of rehabilitation exercises, based on the clinical profile of each patient.

Detailed Description

The aims of this study are to determine safety and feasibility of a prototype EMG-control wearable device (REMO) and to individualise clinical features of stroke survivors able to control the EMG armband targeted to hand rehabilitation. The device REMO consists in an armband composed by 8 bipolar electrodes able to record and process the electromyography of forearm muscles. The patterns of muscle activations are classified and used to perform EMG-biofeedback exercises in stroke rehabilitation training. The device is developed by clinicians of IRCCS San Camillo Hospital and spin-off Morecognition Srl. A total of 100 stroke patients patients has been recruited. They are clinically assessed and then tested on the ability to control the sEMG wearable device. The test is composed of 10 hand and fingers gestures to be performed with the paretic hand. Baseline and activation sEMG signals are recorded and compared for each movement. Three conditions representing absent, partial or full control of the device are defined and logistic multivarialbes regression models are used to identify clinical features describing the group each patient belongs to. Clinical cut-off for each strata is identified by odds ratio.

Registry
clinicaltrials.gov
Start Date
July 25, 2017
End Date
February 27, 2019
Last Updated
4 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
IRCCS San Camillo, Venezia, Italy
Responsible Party
Principal Investigator
Principal Investigator

Andrea Turolla

Laboratory of Rehabilitation Technologies

IRCCS San Camillo, Venezia, Italy

Eligibility Criteria

Inclusion Criteria

  • Single ischemic or haemorrhagic stroke;
  • Score lower than 100 out of a total of 126 at the Functional Independence Measure (FIM) scale

Exclusion Criteria

  • Untreated epilepsy;
  • Major depressive disorder;
  • Fractures;
  • Traumatic Brain Injurj;
  • Severe Ideomotor Apraxia;
  • Severe Neglect;
  • Severe impairment of verbal comprehension.

Outcomes

Primary Outcomes

Fugl-Meyer Upper Extremity (FMA-UE)

Time Frame: within 1 week from enrolment.

Motor function of the upper limb is measured by means of the Fugl-Meyer Scale. There are 3 values: 0 (severe impairment), 1 (moderate impairiment), 2 (preserved function)

Secondary Outcomes

  • Fugl-Meyer - sensation(within 1 week from enrolment.)
  • Fugl-Meyer - pain and Range of Motion(within 1 week from enrolment.)
  • Box and Blocks Test (BBT)(within 1 week from enrolment.)
  • Reaching Performance Scale (RPS)(within 1 week from enrolment.)
  • Modified Ashworth Scale (MAS)(within 1 week from enrolment.)
  • Nine Hole Pegboard Test (NHPT)(within 1 week from enrolment.)
  • Functional Independence Measure scale (FIM)(within 1 week from enrolment.)
  • Number of movements controlled by EMG-biofeedback device(within 1 week from enrolment.)

Study Sites (1)

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