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Effect of painless delivery with epidural analgesia on occurrence postpartum depressio

Phase 4
Completed
Registration Number
CTRI/2021/04/033031
Lead Sponsor
Government Medical College and Hospital Chandigarh
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
62
Inclusion Criteria

American Society of Anesthesiologists (ASA) grade I and II

Age >18 years

Primigravida

Single gestation

Cephalic presentation at >= 37 completed weeks of gestation

In early spontaneous labor (cervical dilation <= 5 cm)

Baseline pain score > 30 (on a 0-100 VAS)

Able to use PCEA pump

Parturient consenting to participate in the study

Exclusion Criteria

Refusal by parturient.

Obesity (weight >100kg)

Parturient who had received oral or parenteral analgesics in the last 4 hours.

Systemic and local sepsis.

Deranged coagulation profile.

Preterm labor ( <37th completed week i.e., <259 days)

Obstetric complications (e.g., premature rupture of amniotic membranes, eclampsia, antepartum hemorrhage).

Foetus with a non-re-assuring non-stress test

Foetus with known or suspected congenital abnormalities

Allergy to study drugs, i.e., levobupivacaine, fentanyl

Patient with Diabetes (either pre-existing or gestational) or history of immunosuppression

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Postpartum depression score using EPDS questionnaire at 6 weeks post-partum.Timepoint: Postpartum depression score using EPDS questionnaire at 6 weeks post-partum.
Secondary Outcome Measures
NameTimeMethod
Maternal satisfaction (VAS) <br/ ><br>Pain score (VAS) <br/ ><br>Sensory and motor block characteristics <br/ ><br>Hemodynamic parameters of mother <br/ ><br>Fetal heart rate <br/ ><br>Duration of second stage of labor <br/ ><br>Mode of delivery <br/ ><br>Apgar scores <br/ ><br>Adverse effects <br/ ><br>Timepoint: During duration of labour
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